Statistical Methods in Biological and Medical Sciences

Edited by

  • C.R. Rao, Pennsylvania State University, University Park, PA, USA
  • R. Chakraborty, University of Texas, Houston, TX, USA

The main purpose of this volume is the dissemination of statistical methodologies in the area of biological and medical sciences. The chapters are written by specialists with considerable experience in the application of statistical techniques for investigating biological and medical issues.

Biological as well as statistical readers will benefit from this exposition.

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Book information

  • Published: November 1991
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-88095-6


...useful as a reference source to anyone wishing to learn about, or update on, any of the specific topics covered in it, and it does provide a very valuable bibliography..
Newsletter of the International Society for Clinical Biostatistics

..the articles...begin beyond the level normally covered in textbooks and give good coverage of recent work in the relevant areas, providing a compact essential reference work.
Mathematical Reviews
... this book successfully brings together a number of subject areas and statistical methodologies ... would provide an excellent starting point for graduate students in early stages of research. It also would be useful to quantitatively aware biological and medical scientists.
Journal of the American Statistical Association
... contains an abundance of reference material. In addition, it is a valuable and stimulating guide both for statisticians and empirically working biologists and medical scientists. As its predecessors, this volume is a must for university libraries and for every researcher working in the mentioned field.
Statistical Papers

Table of Contents

Genetics and Epidemiology. Methods for the Inheritance of Qualitative Traits (J. Rice, R. Neuman, S.O. Moldin). Ascertainment Biases and their Resolution in Biological Surveys (W.J. Ewens). Statistical Considerations in Applications of Path Analysis in Genetic Epidemiology (D.C. Rao). Statistical Methods for Linkage Analysis (G.M. Lathrop, J.M. Lalouel). Statistical Design and Analysis of Epidemiologic Studies: Some Directions of Current Research (N. Breslow). Evolutionary Biology. Robust Classification Procedures and their Applications to Anthropometry (N. Balakishnana, R.S. Ambagaspitiya). Analysis of Population Structure: A Comparative Study of Different Estimators of Wright's Fixation Indices (R. Chakraborty, H. Danker-Hopfe). Estimation of Relationships from Genetic Data (E.A. Thompson). Measurement of Genetic Variation for Evolutionary Studies (R. Chakraborty, C.R. Rao). Statistical Methods for Phylogenetic Tree Reconstruction (N. Saitou). Statistical Models for Sex Ratio Evolution (S. Lessard). Cancer Biology. Stochastic Models of Carcinogenesis (S.H. Moolgavkar). An Application of Score Methodology: Confidence Intervals and Tests of Fit for One-hit Curves (J.J. Gart). Medical Statistics. On Statistical Survival Analysis-I: Kidney-survival Analysis of IgA Nephropathy Patients - A Case Study (O.J.W.F. Kardaun). On Statistical Survival Analysis-II: Confidence Bands for the Survival Function S (t, z) and the Relation with Decision Analysis - Theory (O.J.W.F. Kardaun). Sample Size Determination in Clinical Research (J. Bock, H. Toutenberg)