Handbook of Neuroendocrinology book cover

Handbook of Neuroendocrinology

Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing’s Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.

Audience

Researchers and clinicians in the fields of neuroendocrinology and behavior; graduate students in neuroscience and related disciplines (psychiatry, neuropharmacology, medicine & veterinary medicine); medical residents

Hardbound, 894 Pages

Published: October 2011

Imprint: Academic Press

ISBN: 978-0-12-375097-6

Contents

  • Part I: Basic Principles of Neuroendocrinology
    An introduction to neuroendocrine systems
    Signaling in neuroendocrine systems
    Neuroendocrine Control Systems

    Part II: Neural Regulation of Endocrine Systems
    Evolution of Neurohormones
    Neural control of the anterior lobe of the pituitary gland (pars distalis)
    Neural control of the posterior pituitary gland (neurohypophysis)
    Neural Control of the Intermediate Lobe of the Pituitary Gland (Pars Intermedia) and Proopiomelanocortin
    THE HYPOTHALAMIC PITUITARY ADRENAL AXIS AND NEUROENDOCRINE RESPONSES TO STRESS
    Neuroendocrine Control of Reproduction
    Lifetime Regulation of Growth-Hormone (GH) Secretion
    NEUROENDOCRINE REGULATION OF DEVELOPMENT, GROWTH AND METABOLISM - THYROID
    Circadian Rhythms in Neuroendocrine Systems
    Cardiovascular control - renin angiotensin- AV3V - PVN

    Part III: Hormones, Brain Function and Behavior
    Neuroendocrine Regulation of Food Intake and Energy Homeostasis
    Neuropeptide regulation of stress-induced behavior: insights from the CRF/Urocortin family
    Neuroendocrine regulation of body water and electrolytes: Thirst and salt appetite
    Sexual differentiation of brain and behavior
    Corticosteroid actions on neurotransmission
    Neuroendocrine Mechanism of Puberty
    Sexual behaviors
    Stress and brain function
    Neuroendocrinology of Aggression
    "Chronic Social Stress: Effects on Neuroendocrine Function
    "
    Estrogen and Cognitive Aging in Women: The Critical Period Hypothesis
    Hormones, mood and affect
    Hormones and the aging brain

    Part IV: Neuroendocrine Pathology
    KALLMANN SYNDROME AND OTHER CAUSES OF HYPOTHALAMIC HYPOGONADISM AND RELATED DEVELOPMENT DISORDERS
    Parental Behavior and the Perinatal Programming of Infant Development
    Disorders of the hypothalamic-pituitary- adrenocortical system
    Disorders of the Hypothalamic-Pituitary-Gonadal Axis
    Disorders of the hypothalamic-pituitary- thyroid system
    Neuroendocrine growth disorders - dwarfism - gigantism
    Neuroendocrine inherited or induced aromatase enzyme deficits
    Pituitary adenomas
    Neuroendocrine carcinomas
    Psychoneuroendocrinology

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