Handbook of Heterocyclic Chemistry


  • Alan Katritzky, University of Florida, Gainesville, USA
  • Christopher A. Ramsden, Keele University, Staffordshire, UK
  • John Joule, Emeritus Professor, The University of Manchester, UK
  • Viktor Zhdankin, University of Minnesota Duluth, USA

Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. 
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Suitable for graduate or advanced undergraduate chemistry students and a convenient reference book for researchers and specialists involved in heterocyclic chemistry and other related areas including drug discovery, agrochemicals, and fine chemicals.


Book information

  • Published: August 2010
  • Imprint: ELSEVIER
  • ISBN: 978-0-08-095843-9


"Well into his fifth decade of authoring and editing research articles, books, and reference works on heterocyclic chemistry, Katritzky (Univ. of Florida) continues his bountiful production with this monograph… Three authors review and update the literature, and include references from the late 1990s though the late 2000s… Heterocyclic compounds are very numerous, as is the literature covering them. Given their importance in biochemistry, pharmaceutical chemistry, and the life sciences, this is an important reference work for academic and professional libraries… Highly recommended. Upper-division undergraduates through professionals/practitioners."--CHOICE

Table of Contents

Foreword to the Handbook.
Detailed Contents
Notes on Arrangement of Material in the Handbook.
Explanation of the reference system.

Structure of Heterocycles.
Structure of six-membered rings.
Structure of five-membered rings with one heteroatom.
Structure of five-membered rings with two or more heteroatoms.
Structure of small and large rings.

Reactivity of Heterocycles.
Reactivity of six-membered rings.
Reactivity of five-membered rings with one heteroatom.
Reactivity of five-membered rings with two or more heteroatoms.
Reactivity of small and large rings.

Synthesis of Heterocycles.
Synthesis of monocyclic rings with one heteroatom.
Synthesis of monocyclic rings with two or more heteroatoms.
Synthesis of bicyclic ring systems without ring junction heteroatoms.
Synthesis of tri- and poly-cyclic ring systems without ring junction heteroatoms.
Synthesis of fused ring systems with ring junction heteroatoms.