Handbook of Glycomics book cover

Handbook of Glycomics

This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans.

Audience
biology researchers working in genomics, proteomics, systems biology, bioinformatics and novel therapeutics; glycobiology investigators; students in related areas

Hardbound, 512 Pages

Published: September 2009

Imprint: Academic Press

ISBN: 978-0-12-373600-0

Reviews

  • "Overall, this book is well presented; each chapter contains very valuable figures, an up-to-date bibliography, and tables and charts including 22 color plates at the end of the book. The subject index is useful for fast orientation in the numerous topics discussed in the book. A remarkable feature of this book is very wide range of high_ lighting scientific directions that currently unite in glycomics. This book will no doubt serve as an excellent comprehensive overview and will be handy reference book for scientists and teachers in glycobiology, biochemistry, molecular biology, biotechnology, and medicine."--Biochemistry 2010, Volume 75. No. 8, pp. 1064-65


Contents

  • Introduction to Glycomics

    SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques

    SECTION IV: Glycobioinformatics

    8. Integration of Glycomics Knowledge and Data

    9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures

    10. European Glycomics Portal SECTION V: Glycomes

    11. Glycomics of the Immune System

    12. Mouse and Human

    13. Drosophila

    14. Malaria

    15. Parasitic Worms

    SECTION VI: Disease Glycomes

    16. Cancer Glycomics

    17. An Introduction to Human Disorders of Glycosylation

    18. Summary

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