Guyton and Hall Textbook of Medical Physiology

I. Introduction to physiology: the cell and general physiology

1. Functional organization of the human body and control of the 'internal environment

2. The cell and its functions

3. Genetic control of protein synthesis, cell function, and cell reproduction

II. Membrane physiology, nerve, and muscle

4. The DNA code in the cell nucleus is transferred to an RNA code in the cell cytoplasm -- the process of transcription

5. Membrane potentials and action potentials

6. Contraction of skeletal muscle

7. Excitation of skeletal muscle: neuromuscular transmission and excitation-contraction coupling

8. Contraction and excitation of smooth muscle

III The heart

9. Cardiac muscle: the heart as a pump and function of the heart muscles

10. Rhythmical excitatory and conductive system of the heart

11. The normal electrocardiogram

12. Electrocardiographic interpretation of cardica muscle and coronary blood flow abnormalities: vectrial analysis

13.Cardiac arrhythmias and their electrocardiographic interpretation

IV. The circulation

14. Overview of the circulation; medical biophysics of pressure, flow, and resistance

15. Vascular distensibility and functions of the arterial and venous systems

16. The microcirculation and lymphatic system: capillary fluid exchange, interstitial fluid, and lymph flow

17. Local and humoral control of tissue flow by the tissues

18. Nervous regulation of the circulation, and rapid control of arterial pressure

19. Role of the kidneys in long-term control of arterial pressure and in hypertension: the integrated system for aterial pressure regulation

20. Cardiac output, venous return, and their regulation

21. Muscle blood flow and cardiac output during exercise; the coronary circulation and ischemic heart disease

22. Cardiac failure

23. Heart valves and heart sounds; dynamics of valvular and congenital heart defects

24. Circulatory shock and physiology of its treatment

V. The body fluids and kidneys

25. The body fluids compartments: extracellular and intracellular fluids; intersitial fluid and edema

26. Urine formation by the kidneys: I. Glomerular filtration, renal blood flow, and their control

27. Urine formation by the kidneys: II. Tubular reabsorption and secretion

28. Urine concentration and dilution; regulation of extracellular fluid osmolarity and sodium concentration

29. Renal regulation of potassium, calcium, phosphate, and magnesium; integration of renal mechanisms for control of blood volume and extracellular fluid volume

30. Acid-base regulation

31. Diuretics and kidney diseases

VI. Blood cells, immunity, and blood coagulation

32. Red blood cells, anemia, and polycythemia

33. Resistance of the body to infection: I. Leukocytes, granulocytes, the monocyte-macrophage system, and inflammation

34. Resistance of the body to infection: II. Immunity and allergy

35. Blood types; transfusion; tissue and organ transplanation

36. Hemostasis and blood coagulation

VII. Respiration

37. Pulmonary ventilation

38. Pulmonary circulation, pulmonary edema, pleural fluid

39. Physical principles of gas exchange; diffusion of oxygen and carbon dioxide through the respiratory membrane

40. Transport of oxygen and carbon dioxide in blood and tissue fluids

41. Regulation of respiration

42. Respiratory insufficiency - pathophysiology, diagnosis, oxygen therapy

VIII. Aviation, space, and deep-sea diving physiology

43. Aviation, high-altitude, and space physiology

44. Physiology of deep-sea diving and other hyperbaric conditions

IV. The nervous system: A. General principles and sensory physiology

45. Organization of the nervous system, basic functions of synapses, "Transmitter sybstances"

46. Sensory receptors, neuronal circuits for processing information

47. Somatic sensations: I. General organization, the tactile and position senses

48. Somatic sensations: II. Pain, headache, and thermal sensations

X. The nervous system: B. The special senses

49. The eye: I. Optics of vision

50. The eye: II. Receptor and neural function of the retina

51. The eye: III. Central neurophysiology of vision

52. The sense of hearing

53. The chemical senses - taste and smell

XI. The nervous system: C. Motor and integrative neurophysiology

54. Motor functions of the spinal cord; the cord reflexes

55. Cortical and brain stem control of motor function

56. Contributions of the cerebellum and basal ganglia to overall motor control

57. Cerebral cortex, intellectual functions of the brain, learning and memory

58. Behavioral and motivational mechanisms of the brain - the limbic system and the hypothalamus

59. States of brain activity - sleep, brain waves, epilepsy, psychoses

60. The autonomic nervous system and the adrenal medulla

61. Cerebral blood flow, cerebrospinal fluid, and brain metabolism

XII. Gastrointestinal physiology

62. General principles of gastrointestinal function - motility, nervous control, and blood circulation

63. Propulsion and mixing of food in the alimentary canal

64. Secretory functions of the alimentary tract

65. Digestion and absoprtion in the gastroinestinal tract

66. Physiology of gastrointestinal disorders

XIII. Metabolism and temperature regulation

67. Metabolism of carbohydrates

68. Lipid metabolism

69. Protein metabolism

70. The liver

71. Dietary balances; regulation of feeding; obesity and starvation; vitamins and minerals

72. Energetics and metabolic rate

73. Body temperature, temperature regulation, and fever

XIV. Endocrinology and reproduction

74. Introduction to endocrinology

75. Pituitary hormones and their control by the hypopthalamus

76. Thyroid metabolic hormones

77. Adenocortical hormones

78. Insulin, glucagon, and diabetes mellitus

79. Parathyroid hormone, calcitonin, calcium and phosphate metabolism, vitamin D, bone, and teeth

80. Reproductive and hormonal functions of the mail (and function of the pineal gland)

81. Female physiology before pregnancy and female hormones

82. Pregnancy and lactation

83. Fetal and neonatal physiology

XV. Sports physiology

84. Sports physiology