Genomic Control Process

Development and Evolution

By
  • Eric Davidson, California Institute of Technology, Pasadena, U.S.A.
  • Isabelle Peter, California Institute of Technology, Pasadena, U.S.A.

This book seeks to explore the biological phenomena around genomic regulatory systems which control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the largely phenomenological descriptions of development and evolution by focusing on the causality in these processes, Davidson and Peter provide a much more comprehensive method of considering genomic control across diverse biological processes. The work therefore functions as an explanatory framework for much broader biological considerations.

A continuation of the themes found in the authors’ Regulatory Genome (2006), this book will be essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development.

Audience
Graduate students, post-graduate, and advanced undergraduate students as well as researchers in a variety of disciplines using genomic studies in their work

Hardbound, 352 Pages

Published: September 2013

Imprint: Academic Press

ISBN: 978-0-12-404729-7

Contents

  • 1. The Genome in Development

    2. Transcriptional Control in Development

    3. Genomic Strategies for Early Embryonic Specification

    4. Genomic Strategies for Body Part Formation

    5. Genomic Strategies for Cell Fate Specification

    6. Meta-Analysis of Developmental GRNs

    7. Boolean GRN Models

    8. Evolution: Developmental GRN Hierarchy in the Evolutionary Process

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