Genetic Recombination in Cancer

By

  • Gajanan Sherbet, School of Electrical Electronic and Computer Engineering,University of Newcastle upon Tyne UK and The Institute for Molecular Medicine, Huntington Beach, CA, USA

Genetic recombination is a process of combining genes that leads to the generation of cell variants that possess different characteristics. This process is important to the evolution of a species and to embryonic growth and differentiation. However, this process can also lead to the development of abnormal, cancerous cells. This book reviews the role of genetic recombination in the generation of various cancers and how genetic alterations have been or could be employed to elicit clinically useful information.
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Audience

Researchers, post-graduate and graduate students in molecular medicine, genetics, cancer biology and molecular biology.

 

Book information

  • Published: July 2003
  • Imprint: ACADEMIC PRESS
  • ISBN: 978-0-12-639881-6


Table of Contents

Genetic Integrity, DNA Repair and RecombinationReplication Error (RER) and Genetic InstabilityDNA Repeats, Genetic Recombination and the Pathogenesis of Genetic DisordersChromosomal Recombination in CancerChromosomal Translocation and its Phenotypic OutcomeDNA Methylation and Genetic InstabilityTelomeric DNA and Genetic Instability