Gene Therapy: Prospective Technology assessment in its societal context

Edited by

  • Jörg Niewöhner, Max-Delbrueck Centre, Berlin, Germany
  • Christof Tannert

This book presents work that has been conducted as part of the research project "Discourse on ethical questions of biomedicine" of the interdisciplinary Working Group Bioethics and Science Communication at the Max-Delbrueck-Center for Molecular Medicine (MDC)in Berlin-Buch, Germany. This book offers ground-breaking ideas on how the daily interworking of cutting-edge biomedical research assess the broader social context and its communication to stakeholders and the public. Editors cover three aspects: Scientific, Ethical and Legal, and Perception and Communication. This work establishes an international and interdisciplinary network of excellent researchers at the beginning of their careers, who brilliantly integrate their work into the different perspectives on gene therapy from the natural and social sciences, as well as the humanities and law.
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Practicing scientists, graduate students, academic clinicians who want to understand more about the ethical issues of gene therapy.


Book information

  • Published: July 2006
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-52806-3

Table of Contents

Table of contentsPREFACECHAPTER 1. Editorial Building Interdisciplinarity in Research on Gene TherapySection I Scientific AspectsCHAPTER 2. Identification of genes causing autosomal recessive retinitis pigmentosaCHAPTER 3. Recombinant Adeno-Associated Viral Vectors for CNS Gene TherapyCHAPTER 4. Controlling Adenoviral Gene Transfer in Heart By Catheter Based Coronary PerfusionCHAPTER 5. Biological and cellular barriers limiting the clinical application of nonviral gene deliverysystemsCHAPTER 6. Design, Preparation and Characterization of Polymer-Based Nanocarriers for Non-ViralGene DeliveryCHAPTER 7. Neurogenetic ImagingCHAPTER 8. Implications of Fetal Gene Therapy for the Medical ProfessionSection II Ethical and Legal AspectsCHAPTER 9. Ethical Issues in Gene Therapy Research, An American PerspectiveCHAPTER 10. Do germline interventions justify the restriction of reproductive autonomy?CHAPTER 11. Ghost of Christmas PastEugenics and other moral dilemmas surrounding genetic interventions: a discussion inthe context of virtue ethicsCHAPTER 12. Biomedical Research and Ethical Regulations in China. Some Observations about geneTherapy, Human Research, and Struggles of InterestCHAPTER 13. Does patent granting hinder the development of Gene Therapy products?CHAPTER 14. On The Political Side of Gene Therapy. What Can Be Drawn from the French Situation?Section III Perception and CommunicationCHAPTER 15. How to Communicate Risks in Gene Therapy?CHAPTER 16. European analysis of the various procedure existing to interrupt a clinical research protocolthanks to a French example of gene therapyCHAPTER 17. The future of public perception of gene therapy in Europe, an educated guess