Gap Junctions: Molecular Basis of Cell Communication in Health and Disease, 49

  • Arnost Kleinzeller, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.
    • Fambrough Douglas
      • Dale Benos, Department of Physiology and Biophysics, University of Alabama, Birmingham, Alabama, U.S.A.
        • Camillo Peracchia, University of Rochester, New York, U.S.A.


        Biophysicists, cell biologists, physiologists, and pathologists.


Book information

  • Published: December 1999
  • ISBN: 978-0-12-153349-6

Table of Contents

Channel Structure, Assembly, and Degradation:Gap Junction Structure: New Structures and New Insights, G. Sosinsky.Degradation of Gap Junctions and Connnexins, J.G. Laing and E.C. Beyer.Channel Forms, Permeability, and Conductance:Homotypic, Heterotypic, and Heteromeric Gap Junction Channels, P.R. Brink, V. Valiunas, and G.J. Christ.Heteromultimeric Gap Junction Channels and Cardiac Disease, S. Elenes and A.P. Moreno.Ion Permeation through Connexin Gap Junction Channels: Effects on Conductance and Selectivity, R.D. Veenstra.Phosphorylation of Connexins: Consequences for Permeability, Conductance, and Kinetics of Gap Junction Channels, H.J. Jongsma, H.V.M. van Rijen, B.R. Kwak, and M. Chanson.Intercellular Calcium Wave Communication via Gap Junction-Dependent and -Independent Mechanisms, E. Scemes, S.O. Suadicani, and D.C. Spray.Voltage Grating:Membrane Potential Dependence of Gap Junctions in Vertebrates, L.C. Barrio, A. Revilla, J.M. Goméz-Hernandez, M. de Miguel, and G. González.A Reexamination of Calcium Effects on Gap Junctions in Heart Myocytes, B. Delage and J. Délèze.Chemical Grating:Distinct Behaviors of Chemical- and Voltage-Sensitive Gates of Gap Junction Channel, F.F. Bukauskas and C. Peracchia.A Molecular Model for the Chemical Regulation of Connexin43 Channels: The "Ball-and-Chain" Hypothesis, M. Delmar, K. Stergiopoulos, Nobuo Homma, G. Calero, G. Morley, J.F. Ek-Vitorin, and S.M. Taffet.Mechanistic Differences between Chemical and Electrical Gating of Gap Junctions, I.M. Skerrett, J.F. Smith, and B.J. Nicholson.Behavior of Chemical- and Slow Voltage-Sensitive Gates of Connexin Channels: the "Cork" Gating Hypothesis, C. Peracchia, X.G. Wang, and L.L. Peracchia.Molecular Determinants of Voltage Gating of Gap Junctions Formed by Connexin32 and 26, T.A. Bargiello, S. Oh, Y. Ri, P.E. Purnick, and V.K. Verselis.Regulation of Connexin43 by Tyrosine Protein Kinases, A.F. Lau, B. Warn-Cramer, and R. Lin.Gating of Gap Junction Channels and Hemichannels in the Lens: A Role in Cataract?, R. Eckert, P. Donaldson, J. Lin, J. Bond, C. Green, R. Merriman-Smith, M. Tunstall, and J. Kistler.Hemichannels:Biophysical Properties of Hemi-Gap-Junctional Channels Expressed in XenopusOocytes, L. Ebihara and J. Pal.Properties of Connexin50 Hemichannels Expressed in Xenopus laevisOocytes, S. Eskandari and G.A. Zampighi.Invertebrate Gap Junctions:Gap Junction Communication in Invertbrates: The Innexin Gene Family, P. Phelan.Diseases Based on Defects of Cell Communication:Hereditary Human Diseases Caused by Connexin Mutations, M.V.L. Bennett and C.K. Abrams.Trafficking and Targeting of Connexin32 Mutations to Gap Junctions in Charcot-Marie-Tooth X-Linked Disease, P.E.M. Martin and W.H. Evans.Molecular Basis of Deafness Due to Mutations in the Connexin26 Gene (GJB2), X. Estivill and R. Rabionet."Negative: Physiology: What Connexin-Deficient Mice Reveal about the Functional Roles of Individual Gap Junction Proteins, D.C. Spray, T. Kojima, E. Scemes, S.O. Suadicani, Y. Gao, S. Zhao, and A. Fort.Role of Gap Junctions in Cellular Growth Control and Neoplasia: Evidence and Mechanisms, R.J. Ruch.Gap Junctions in Inflammatory Responses: Connexins, Regulation, and Possible Functional Roles, J.C. Sáez, R. Araya, M.C. Branes, M. Concha, J.E. Contreras, E.A. Eugenín, A.D. Martínez, F. Palisson, and M.A. Sepúlveda.Cx43 (a1) Gap Junctions in Cardiac Development and Disease, R.G. Gourdie and C.W. Lo.Gap Junctional Communication in the Failing Heart, W.C. De Mello.Gap Junctions Are Specifically Disrupted by Trypanosoma cruzi Infection, R.C.S. Goldenberg, A. Gonçalves, and A.C. Campos de Carvalho.Index.