G Protein Coupled Receptors book cover

G Protein Coupled Receptors

Trafficking and Oligomerization

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as G protein-coupled receptor trafficking motifs, structure-based virtual screening, and automation-friendly high throughput assays for identification of pharmacoperone drugs.

Audience
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Included in series
Methods in Enzymology

Hardbound, 480 Pages

Published: February 2013

Imprint: Academic Press

ISBN: 978-0-12-391862-8

Contents

    1. GPCR Trafficking

      1. Therapeutic Rescue of Misfolded/Mistrafficked Mutants: Automation-Friendly High Throughput Assays for Identification of Pharmacoperone Drugs of GPCRs
      2. David C. Smithson, Jo Ann Janovick, P. Michael Conn

      3. Trafficking of the Follitropin Receptor
      4. Alfredo Ulloa-Aguirre, James A. Dias, George Bousfield, Ilpo Huhtaniemi, and Eric Reiter

      5. Single Molecule Imaging Technique to Study the Dynamic Regulation of GPCR Function at the Plasma Membrane
      6. B.E. Snaar-Jagalska, A. Cambi, T. Schmidt and S. de Keijzer

      7. GPCR Oligomerization and Receptor Trafficking
      8. Richard J. Ward, Tian-Rui Xu and Graeme Milligan

      9. b-Arrestins and G Protein-Coupled Receptor Trafficking
      10. Dong Soo Kang, Xufan Tian, and Jeffrey L. Benovic

      11. Tracking Cell Surface Mobility of GPCRs Using α-Bungarotoxin Linked Fluorophores
      12. Saad Hannan, Megan E Wilkins, P Thomas and Trevor G Smart

      13. Regulatory Mechanism of G Protein-Coupled Receptor Trafficking to the Plasma Membrane: A Role for mRNA Localization
      14. Kusumam Joseph, Eleanor K. Spicer and Baby G. Tholanikunnel

      15. Dissecting Trafficking and Signaling of Atypical Chemokine Receptors
      16. Elena Borroni, Cinzia Cancellieri, Massimo Locati, Raffaella Bonecchi


        Trafficking Motifs

      17. Systematic and Quantitative Analysis of G Protein-Coupled Receptor Trafficking Motifs
      18. Carl M. Hurt, Vincent K. Ho, and Timothy Angelotti

      19. Identification of Endoplasmic Reticulum Export Motifs for G Protein-Coupled Receptors
      20. Guangyu Wu

      21. Amino Acid Residues of G-Protein Coupled Receptors Critical for Endoplasmic Reticulum Export and Trafficking
      22. Motonao Nakamura, Daisuke Yasuda, Nobuaki Hirota, Teruyasu Yamamoto, Satoshi Yamaguchi, Takao Shimizu and Teruyuki Nagamune

        GPCR Oligomerization

      23. G Protein-Coupled Heteromers Regulation in Disease
      24. Ivone Gomes, Achla Gupta and Lakshmi A. Devi

      25. Hetero-Oligomerization and Specificity Changes of G Protein-Coupled Purinergic Receptors: Novel Insight into Diversification of Signal Transduction
      26. Tokiko Suzuki, Kazunori Namba, Natsumi Mizuno and Hiroyasu Nakata

      27. Bimolecular Fluorescence Complementation Analysis of G Protein-Coupled Receptor Dimerization in Living Cells
      28. Karin F.K. Ejendal, Jason M. Conley, Chang-Deng Hu, and Val J. Watts

      29. G-Protein Coupled Receptor Heterodimerization in the Brain
      30. Dasiel O. Borroto-Escuela, Wilber Romero-Fernandez, Pere Garriga, Francisco Ciruela, Manuel Narvaez, Alexander O. Tarakanov, Miklós Palkovits, Luigi F. Agnati and Kjell Fuxe

      31. Experimental Strategies for Studying G Protein-Coupled Receptor Homo- and Heteromerization with Radioligand Binding and Signal Transduction Methods
      32. Roberto Maggio, Cristina Rocchi, and Marco Scarselli

      33. Analysis of GPCRs Dimerization Using Acceptor Photobleaching Resonance Energy Transfer Techniques
      34. Marta Busnelli, Mario Mauri, Marco Parenti and Bice Chini

      35. Techniques for the Discovery of GPCR-Associated Protein Complexes
      36. Avais Daulat , Pascal Maurice and Ralf Jockers

      37. Expression, Purification and Analysis of GProtein-Coupled Receptor Kinases
      38. Rachel Sterne-Marr, Alison I. Baillargeon, Kevin R. Michalski, and John J. G. Tesmer

      39. Modern Methods to Investigate the Oligomerization of Glycoprotein Hormone Receptors (TSHR,LHR, FSHR)

      Marco Bonomi and Luca Persani

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