Fundamentals of Forensic DNA Typing book cover

Fundamentals of Forensic DNA Typing

Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.

Audience

Undergraduate forensic science students, lawyers who need enough cursory information to understand and speak to jury, law enforcement, crime scene investigators, legal professionals and government/legal policy makers.

Paperback, 520 Pages

Published: August 2009

Imprint: Academic Press

ISBN: 978-0-12-374999-4

Reviews

  • "There is perhaps no individual better suited to author a foundational survey of forensic DNA typing than John Butler. As with past editions, Butler’s knowledge, along with his organizational and communication skills make Fundamentals of Forensic DNA Typing a must read for students, forensic practitioners and trial attorneys. This text provides the reader with insightful and understandable explanations necessary to comprehend the underpinnings of forensic DNA analysis. It continues in the tradition of its predecessors as the premier textbook on the forensic DNA subject."
    - Richard Saferstein, Ph.D. Author and Forensic Science Consultant

    "When ScienceWatch.com, a Thomson Reuters web resource for measuring and analyzing science trends, recently listed the most influential institutions and researchers in forensic science based on journal citations, the National Institute of Standards and Technology (NIST) and one of its researchers, John Butler, were among the leaders."--ThomasNet.com

    "Intended as the companion to the 2010 publication, Fundamentals of Forensic DNA Typing, this title contains 18 chapters with four appendices providing up-to-date coverage of essential topics in the field of DNA analysis. The book includes new information on DNA databases, low-level DNA, and validation; a comprehensive listing of alleles for the 23 STR loci present in commercial kits, and coverage of familial searching."--Evidence Technology Magazine, July-August 2012, page 4


Contents


  • Foreword

    Introduction

    Acknowledgments

    About the Author

    Chapter 1 Overview and History of DNA Typing

    Chapter 2 Basics of DNA Biology and Genetics

    Chapter 3 Historical Methods

    Chapter 4 Sample Collection, Storage, and Characterization

    Chapter 5 DNA Extraction

    Chapter 6 DNA Quantitation

    Chapter 7 DNA Amplification (The Polymerase Chain Reaction)

    Chapter 8 Short Tandem Repeat Markers

    Chapter 9 Fundamentals of DNA Separation and Detection

    Chapter 10 STR Genotyping and Data Interpretation

    Chapter 11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence

    Chapter 12 DNA Databases

    Chapter 13 Quality Assurance

    Chapter 14 Forensic Challenges: Degraded DNA, Mixtures, and LCN

    Chapter 15 Additional Loci and Nonhuman DNA Testing

    Chapter 16 Lineage Markers: Y Chromosome and mtDNA Testing

    Chapter 17 Applications of DNA Typing

    Chapter 18 Future Trends

    Appendix 1 Glossary of Terms

    Appendix 2 Useful Web Sites

    Appendix 3 Probability and Statistics

    Index

    References are provided at the end of each chapter by subtopic (but without direct

    citation within the text).

    High-profile cases and other interesting information are included as D.N.A. (Data,

    Notes, and Applications) boxes scattered throughout the book in the chapter pertaining

    to a particular subject.


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