Fundamental Neuroscience book cover

Fundamental Neuroscience

The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book has been retooled to better serve its audience in the neuroscience and medical communities.The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover.

Graduate students in neuroscience, neuroanatomy and neurophysiology, and neurobiology. The secondary market for this book is researchers in neuroscience primarily, but also in the related fields of psychology, cell biology, molecular biology, genetics and any other areas of science with cross over into neuroscience research.

Hardbound, 1152 Pages

Published: November 2012

Imprint: Academic Press

ISBN: 978-0-12-385870-2


  • "Here in the fourth edition of this textbook, editors Squire, Berg, Bloom, du Lac, Ghosh, and Spitzer, all working scientists with backgrounds in various specialties in neuroscience, present extensive new material with all chapters updated and rewritten. The book is organized into seven sections with numerous chapters in each encompassing a comprehensive view of 21st century neuroscience…"--Reference & Research Book News, December 2013


  • List of Boxes
    Preface to the Fourth Edition
    About the Editors

    1. Fundamentals of Neuroscience
    Floyd E. Bloom
    2. Basic Plan of the Nervous System
    Larry W. Swanson

    3. Cellular Components of Nervous Tissue
    Patrick R. Hof, Grahame Kidd, Javier DeFelipe, Jean de Vellis, Miguel A. Gama Sosa, Gregory A. Elder, and Bruce D. Trapp
    4. Subcellular Organization of the Nervous System: Organelles and Their Functions
    Scott T. Brady, David R. Colman, and Peter J. Brophy
    5. Membrane Potential and Action Potential
    David A. McCormick
    6. Neurotransmitters
    Ariel Y. Deutch
    7. Release of Neurotransmitters
    Thomas L. Schwarz
    8. Neurotransmitter Receptors
    M. Neal Waxham
    9. Intracellular Signaling
    Howard Schulman
    10. Postsynaptic Potentials and Synaptic Integration
    John H. Byrne
    11. Information Processing in Dendrites and Spines
    Nelson Spruston, Michael Hausser, and Greg Stuart
    12. Brain Energy Metabolism
    Igor Allaman and Pierre J. Magistretti

    13. Neural Induction and Pattern Formation
    Andrew Lumsden and Clemens Kiecker
    14. Cellular Determination
    William A. Harris, Volker Hartenstein, and Martyn Goulding
    15. Neurogenesis and Migration
    Marianne Bronner and Mary E. Hatten
    16. Growth Cones and Axon Pathfinding
    Alex L. Kolodkin and Marc Tessier-Lavigne
    17. Synapse Formation
    Steven J. Burden and Peter Scheiffele
    18. Programmed Cell Death and Neurotrophic Factors
    Ronald W. Oppenheim, Carolanne E. Milligan, and Christopher S. von Bartheld
    19. Synapse Elimination
    Juan C. Tapia and Jeff W. Lichtman
    20. Dendritic Development
    Hollis Cline, Anirvan Ghosh, Yuh-Nung Jan, and Josh Sanes
    21. Early Experience and Sensitive Periods
    Eric I. Knudsen

    22. Fundamentals of Sensory Systems
    Stewart H. Hendry and Steven S. Hsiao
    23. Chemical Senses: Taste and Olfaction
    Kristin Scott
    24. The Somatosensory System
    Stewart Hendry and Steven Hsiao
    25. Audition
    M. Christian Brown and Joseph Santos-Sacchi
    26. Vision
    R. Clay Reid and W. Martin Usrey

    Section V: MOTOR SYSTEMS
    27. Fundamentals of Motor Systems
    Sten Grillner
    28. The Spinal and Peripheral Motor System
    George Z. Mentis
    29. Control of Movement
    Marc H. Schieber and James F. Baker
    30. The Basal Ganglia
    Jonathan W. Mink
    31. Cerebellum
    Martha Bagnall, Sascha du Lac, and Michael Mauk
    32. Eye Movements
    Richard J. Krauzlis

    33. The Hypothalamus: An Overview of Regulatory Systems
    J. Patrick Card and Larry W. Swanson
    34. Central Control of Autonomic Functions: Organization of the Autonomic Nervous System
    Terry L. Powley
    35. Neural Control of Respiratory and Cardiovascular Functions
    J.L. Feldman, D.R. McCrimmon, and S.F. Morrison
    36. Food Intake and Metabolism
    Stephen C. Woods and Edward M. Stricker
    37. Water and Salt Intake and Body Fluid Homeostasis
    Edward M. Stricker and Joseph G. Verbalis
    38. Neuroendocrine Systems
    Andrea C. Gore
    39. Circadian Timekeeping
    David R. Weaver and Patrick Emery
    40. The Neurobiology of Sleep and Dreaming
    Edward F. Pace-Schott and J. Allan Hobson
    41. Reward, Motivation, and Addiction
    George F. Koob, Barry J. Everitt, and Trevor W. Robbins

    42. Human Brain Evolution
    Jon H. Kaas and Todd M. Preuss
    43. Cognitive Development and Aging
    Peter R. Rapp and Jocelyne Bachevalier
    44. Visual Perception of Objects
    Andrew H. Bell, Luiz Pessoa, Roger B.H. Tootell, and Leslie G. Ungerleider
    45. Spatial Cognition
    Carl R. Olson and Carol L. Colby
    46. Attention
    John H. Reynolds, Jacqueline P. Gottlieb, and Sabine Kastner
    47. Learning and Memory: Basic Mechanisms
    John H. Byrne
    48. Learning and Memory: Brain Systems
    Joseph R. Manns and Elizabeth A. Buffalo
    49. Language
    David N. Caplan and James L. Gould
    50. The Prefrontal Cortex and Executive Brain Functions
    Earl K. Miller and Jonathan D. Wallis
    51. The Neuroscience of Consciousness
    Christof Koch



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