Fetal and Neonatal Neurology and Neurosurgery

By
  • Malcolm Levene, MD, FRCP, FRCPCH, FMedSc, Professor of Pediatrics and Child Health, Division of Paediatrics and Child Health, University of Leeds, Leeds General Infirmary, Leeds, UK
  • Frank Chervenak, MD, FACOG, MMM, Given Foundation Professor and Chairman, Department of Obstetrics and Gynecology, New York Weill Cornell Medical Center, New York, NY, USA

This book provides a definitive reference work on the developing brain, from conception through the first year of life. Its purpose is to provide the range of specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system, so that they can provide prompt and informed treatment of neurological disability – the most feared complication of pregnancy and the early months of the life of the newborn child.

Audience
Specialists in fetal medicine, Neonatologists, General paediatricians, Paediatric neurosurgeons, Paediatric neurologists

Hardbound, 960 Pages

Published: January 2009

Imprint: Churchill Livingstone

ISBN: 978-0-443-10407-7

Reviews

  • "The book has 88 contributors from all over the world, who under the guidance of the two editors have made a wonderful comprehensive book...it should be found on the shelf of every neonatal department or unit."
    International Journal of Adolescent Medicine and Health, 2009

Contents

  • SECTION I Structural Development of the CNS

    1. The molecular basis of brain development
    2. Early embryonic development of the brain
    3. Development of consciousness: fetal, neonatal and maternal interactions
    4. Ultrasound assessment of normal fetal brain development
    5. MR imaging of the fetal central nervous system
    6. Imaging the neonatal brain

    SECTION II Functional Assessment of CNS Development

    7. Functional assessment of the fetal CNS
    8. The development of senses
    9. Clinical assessment of the infant nervous system
    10. Perinatal cerebral circulation
    11. Cerebral blood flow and energy metabolism in the developing brain
    12. EEG and evoked potentials in the neonatal period

    SECTION III Anomalies

    13. Congenital structural defects of the brain
    14. Genetics of neurodevelopmental anomalies
    15. Antenatal assessment of CNS anomalies, including neural tube defects
    16. Transvaginal fetal neuroscan
    17. Epidemiology and prevention of neural tube defects

    SECTION IV Hemorrhagic and Ischemic Lesions

    18. Fetal brain injury and multiple pregnancies
    19. Infection, inflammation and brain injury
    20. Neonatal intracranial hemorrhage
    21. Cerebral ischemic lesions

    SECTION V Perinatal Asphyxia

    22. Pathophysiology of asphyxia
    23. Antenatal prediction of asphyxia
    24. Intrapartum monitoring for asphyxia
    25. Prediction of asphyxia with fetal gas analysis
    26. The asphyxiated newborn infant
    27. Neuroprotection of the fetal and neonatal brain
    28. Medico-legal issues: The United Kingdom perspective
    29. Malpractice issues in perinatal medicine: The United States perspective

    SECTION VI Infection of the CNS

    30. Toxoplasmosis
    31. Congenital viral infections and the central nervous system
    32. Bacterial and fungal infections

    SECTION VII Metabolic Disorders

    33. Inborn errors of metabolism presenting with encephalopathy

    SECTION VIII Seizure Disorders

    34. Seizure disorders of the neonate
    35. Hypoglycemia and brain injury - when neonatal metabolic adaptation fails
    36. Kernicterus

    SECTION IX the Special Senses

    37. Disorders of vision
    38. Hearing disorders

    SECTION X Disorders of the Nerve and Muscle

    39. Disorders of the spinal cord, cranial and peripheral nerves
    40. Neuromuscular disorders

    SECTION XI Hydrocephalus and Neurosurgery

    41. Fetal neurosurgical interventions
    42. Neonatal hydrocephalus – clinical assessment and non-surgical treatment
    43. Neurosurgical management of hydrocephalus
    44. Surgical management of neural tube defects
    45. Congenital defects, vascular malformations and other lesions

    SECTION XII Epidemiology of Neurologic Disability

    46. The epidemiology of the cerebral palsies
    47. The epidemiology of intellectual disabilities

    SECTION XIII Ethical Dilemmas

    48. Issues for the obstetrician
    49. Issues for the neonatologist

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