Essentials of Medical Biochemistry

With Clinical Cases


  • N. V. Bhagavan, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
  • Chung-Eun Ha, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
  • N. V. Bhagavan, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA

Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor.
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Students in biochemistry and related premed and health care programs taking a ONE semester course from books identified in competition. Medical students will use this book primarily as a refresher to meet USMLE requirements. This is a subset of the general biochemistry market, which is the 3rd largest market in chemistry (after introductory chemistry and organic chemistry).


Book information

  • Published: January 2011
  • ISBN: 978-0-12-095461-2


"The contents of the book are quite up to date. The book covers basic, traditional biochemical topics as well as recently developments driven by genomics that caught the interests of everyone, including biochemist and health care personnels and future doctors. Adopting such a concise textbook that covers the many aspects of biochemistry and their relevantness to diseases would prepare our pre-med students with a broad understanding of the mechanisms of a large number of health problems. The book would also be a very useful starting point for those who are experts in other field of basic research but have an interest or need to relate basic biochemical processes to and disease mechanisms in a broad range...This book is very concise on most of the topics it covers. It describes the principles to the point the students need without lengthy elaborations that takes too much time that students often find hard to find due to heavy study load. Accompanied by case studies, this is a very good book for medical orientated students." -Dr. Yuzhu Zhang Department of Biology, Chemistry, and Physics Illinios Institute of Technology "The writing style is in general easy to read and the topics that I have reviewed seemed to be explained well." -Dr. William E. Seifert Department of Biochemistry & Molecular Biology Purdue University "We adopted the Bhagavan text because it is the most comprehensive and authoritative text on the market and is suitable for our students who have already had at least one semester of biochemistry prior to acceptance in medical school...The chapters on genomics and hematology are handled better by Bhagavan than in other books that I'm familiar with. It was probably this coverage in Bhagavan that made it our choice. The hematology section is better than that in most full hematology books." -Dr. Eugene Allanson Department of Biochemistry and Molecular Biology Georgetown University Medical Center

Table of Contents

1. Cells - Structures and Functions
2. Water, Acids, Bases, and Buffers
3. Amino Acids
4. Three-Dimensional Structure of Proteins
5. Energetics of Biological Systems
6. Enzymes and Enzyme Regulation
7. Clinical Enzymology and Biomarkers of Tissue Injury
8. Simple Carbohydrates
9. Heteropolysaccharides I: Glycoconjugates, Glycoproteins and Glycolipids
10. Connective Tissue: Fibrous and Non-Fibrous Proteins and Proteoglycans
11. Gastroentestinal Digestion and Absorption
12. Carbohydrate Metabolism I: Glycolysis and TCA Cycle
13. Electron Transport Chain, Oxidative Phosphorylation, and Other Oxygen-consuming Systems
14. Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways
15. Protein and Amino Acid Metabolism
16. Lipids I: Fatty Acids and Eicosanoids
17. Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
18. Lipids III: Plasma Lipoproteins
19. Contractile Systems
20. Perturbations of Energy Metabolism: Obesity and Diabetes Mellitus
21. Structure and properties of DNA
22. DNA Replication, Repair, and Mutagenesis
23. RNA and Protein Synthesis
24. Regulation of Gene Expression
25. Nucleotide Metabolism
26. Hemoglobin
27. Metabolism of Iron and Heme
28. Endocrine Metabolism I: Introduction and Signal Transduction
29. Endocrine Metabolism II: Hypothalamus and Pituitary
30. Endocrine Metabolism III: Adrenal Glands
31. Endocrine Metabolism IV: Thyroid Gland
32. Endocrine Metabolism V: Reproductive System
33. Immunology
34. Biochemistry of Hemostasis
35. Mineral Metabolism
36. Vitamin Metabolism
37. Water, Electrolytes, and Acid-Base Balance
38. Case Studies