Escherichia coli
Pathotypes and Principles of Pathogenesis
Edited by- Michael Donnenberg, University of Maryland School of Medicine, Baltimore, U.S.A.
The second edition of Escherichia coli: Pathogenesis and Pathotypes is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. This work concludes with a presentation of virulence factors, common to two or more pathotypes. The book is a great resource for references and up-to-date knowledge for anyone who studies E. coli pathogenesis, either as established investigators or investigators new to the field. It is also an excellent text for those who teach mechanisms of pathogenesis to graduate students and medical students and wish to have a source of knowledge from which to develop lectures.
Audience
Microbiologists, cell biologists, infectious disease clinicians, food safety experts, veterinarians, and advanced students.
Hardbound, 480 Pages
Published: August 2013
Imprint: Academic Press
ISBN: 978-0-12-397048-0
Reviews
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Previous Edition Praise
"...a thorough, timely treatise on the current state of the field for researchers and advanced graduate students in bacterial pathogenesis. It is also an excellent and valuable reference work of general interest to microbiologists, infectious disease specialists, and food safety experts, and should be included in microbiology and medical reference libraries."--ASM NEWS
"...a very informative book which is well presented and would be excellent value for money for scientists generally interested in the basis of microbial pathogenesis, as well as E. coli specifically."--MICROBIOLOGY TODAY
Contents
- Section I: Escherichia coli, the Organism
The Biology and Ecology of Pathogenic E. coli
Comparative Genomics of Pathogenic E. coli
Evolution of Pathogenic E. coli
Section II: Escherichai coli Pathotypes
Enteropathogenic E. coli
Enterohemorrhagic and other Shiga-toxin Producing E. coli
Enterotoxigenic E. coli
Shigella and Enteroinvasive E. coli
Enteroaggregative E. coli
Uropathogenic E. coli
Meningitis-Associated E. coli
Hybrid and Potentially Pathogenic E. coli strains
Section III: Escherichia coli Virulence Factors
Adhesive Pili of the Chaperone-Usher Family
Type IV Pili and Type 2 Secretion Systems
Type 3 Secretion Systems
Type 3 Secretion Effectors
Types 1 and 5 Secretion Systems and Toxins
Capsule and Lipopolysaccharide
