Epilepsy Part I: Basic Principles and Diagnosis

Handbook of Clinical Neurology

Edited by

  • Hermann Stefan, Director of Epilepsy Centre, Neurological Clinic, University Hospital, Erlangen, Germany
  • William Theodore, Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, and Uniformed Services University of the Health Sciences, Bethesda, MD, USA

Epilepsy, Part I, Basic Principles and Diagnosis, Volume 107, in the Handbook of Clinical Neurology series offers a comprehensive review of our knowledge of the field today, including epidemiology, basic mechanisms, animal models, and topics of increasing interest such as the role of inflammation in epilepsy. It provides a comprehensive approach to description of the clinical, electrographic and imaging aspects of the epilepsies, with a clear outline of contemporary classification and the role of modern diagnostic techniques, as well as neuropsychological and psychiatric aspects of epilepsy. Chapters are authored by internationally respected neurologists with varied perspectives insuring depth to the content. Epilepsy, Part II, Treatment, Volume 108, continues coverage of epilepsy with a focus on treatment. The volumes will be a very important resource for basic scientists, clinical investigators, and all health professionals treating patients with epilepsy.
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Clinical neurologists and research neuroscientists


Book information

  • Published: October 2012
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-52898-8


"Stefan…and Theodore…present the first of two volumes for clinicians and neuroscientists on the clinical features and management of the neurological manifestations of epilepsy…neurologists, neuroscientists, epilepsy specialists, geneticists, and neurosurgeons from North America, Europe, Australia, and Japan address basic mechanisms;… the diagnosis of various types; …and various types of imaging. "--Reference & Research Book News, December 2013

Table of Contents

1. Molecular Basis of Acquired Epileptogenesis - K. Lukasiuk and A. Pitk√§nen (Warsaw, Poland and Kuopio, Finland)   
2. Cellular bases of focal and generalised epilepsies - P.A. Schwartzkroin (Davis, USA)
3. Epilepsy as a dynamic disease of neuronal networks - F.H. Lopes Da Silva, J.A. Gorter and W.J. Wadman (Amsterdam, The Netherlands)
4. Animal models - A. Coppola and S.L. Moshé (Bronx, USA and Naples, Italy)
5. Classification of epilepsies and seizures: historical perspective and future directions - A.T. Berg and H. Cross (Chicago, USA and London, UK)
6. The epidemiology of the epilepsies - A. Neligan, W.A. Hauser and J.W. Sander (London, UK, New York, USA and Heemstede, The Netherlands)
7. Maturation of the human brain and epilepsy - G.L. Holmes, M.D.M. Milh and O. Dulac (Lebanon, USA, Marseille, France and Paris, France)
8. Genetics of idiopathic epilepsies - O.K. Steinlein (Munich, Germany)
9. The genetics of focal epilepsies - J.J. Poza (San Sebasti√°n, Spain)
10. Inflammation and epilepsy - A. Vezzani, S. Balosso and T. Ravizza (Milan, Italy)

11. Age related epileptic encephalopathies - R. Guerrini and J.M. Pellock (Florence, Italy and Richmond, USA)
12. Epileptic syndromes with focal seizures of childhood and adolescence - T. Loddenkemper, E. Wyllie and E. Hirsch (Cleveland, USA, Boston, USA and Strasbourg, France)
13. Idiopathic generalised epilepsies - A. Kao and P.M. Rao (Washington, USA)
14. Temporal lobe epilepsy - M. Thom and E.H. Bertram (London, UK and Charlottesville, USA)
15. Extratemporal epilepsies - S. Bauer and H.M. Hamer (Marburg, Germany)
16. Reflex epilepsies - P. Wolf and M. Koepp (Dianalund, Denmark and London, UK)
17. Psychogenic nonepileptic seizures - P. Widdess-Walsh, B. Mostacci, P. Tinuper and O. Devinsky (Livingston and New York, USA and Bologna, Italy)
18. Syncope - B.A. Engelsen (Bergen, Norway)
19. Sleep and epilepsy - P. Hal√°sz (Budapest, Hungary)
20. Electroencephalography and video-electroencephalography - A. Gil-Nagel and B. Abou-Khalil (Madrid, Spain and Nashville, USA)
21. Magnetoencephalography - H. Stefan, N. Nakasato and A.C. Papanicolaou (Erlangen, Germany; Sendai, Japan and Houston, USA)
22. Structural brain imaging - R. Kälviäinen and Arnd Dörfler (Kuopio, Finland and Erlangen, Germany)
23. Functional MR imaging: focus localisation - G.D. Jackson, R. Badawy and J. Gotman (Heidelberg and Melbourne, Australia and Montreal, Canada)
24. Functional MR: functional mapping - W.D. Gaillard and M.M. Berl (Washington and Bethesda, USA)
25. Magnetic resonance spectroscopy in epilepsy - T. Hammen and R. Kuzniecky (Erlangen, Germany and New York, USA)
26. Epilepsy diagnosis: PET - H.T. Chugani, F. Semah, A. Kumar and W.H. Theodore (Detroit, USA; Lille, France and Bethesda, USA)
27. Per-ictal single photon emission computed tomography: principles and applications in epilepsy evaluation - E.L. So and T.J. O’Brien (Rochester, USA and Melbourne, Australia)
28. Clinical neuropsychology in epilepsy: theoretical and practical issues - C. Helmstaedter and J-A. Witt (Bonn, Germany)
29. Neuropsychiatric complications of epilepsy - D.C. Hesdorffer and A.M. Kanner (New York and Chicago, USA)