Eosinophils in Health and Disease
Edited by- James Lee, Consultant, Division of Pulmonary Medicine, Associate Professor, Department of Biochemistry and Molecular Biology , Distinguished Mayo Clinic Investigator, Mayo Clinic, Scottsdale, Arizona, USA
- Helene Rosenberg, Senior Investigator and Section Chief, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Written and edited by leaders in the field, Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. Despite an explosion of discovery in this area over the last decade, this is the only up-to-date resource on eosinophils and eosinophilia exists. This full-color volume provides an essential collection of world class information that is a must-have for any immunologists workbench or bookshelf.
Audience
Researchers, clinical investigators and advanced students in the fields of immunology, autoimmunity, asthma and allergy research and cell biology.
Hardbound, 678 Pages
Published: November 2012
Imprint: Academic Press
ISBN: 978-0-12-394385-9
Contents
Dedication
Preface
I Historical Overview and Perspective
II Evolutionary Origins of EosinophilsIII Eosinophil Structure
IV Ex Vivo Models for the Study of EosinophilsV Eosinophilopoeisis
VI Eosinophil TraffickingVII Eosinophil Signal Tranduction
VIII Eosinophil Secretory FunctionsIX Eosinophils and anti-Pathogen Host Defense
X Anti-fungal host defenseXI Eosinophils as Regulators of Physiological Homeostasis
XII Eosinophil cell-cell communicationXIII Eosinophil-mediated Tissue Remodeling and Fibrosis
XIV The Roles of Eosinophils in Human DiseasesXV Eosinophils and Disease: Animal models of human pathology
XVI Anti-eosinophil therapeuticsXVII Emerging Concepts
ConclusionsAcknowledgements
