C.A. Rohl and R.L. Baldwin, Deciphering Rules of Helix Stability in Peptides.N.R. Kallenbach and E.J. Spek, Modified Amino Acids as Probes of Helix Stability.V.J. LiCata and N.M. Allewell, Measuring Hydration Changes of Proteins in Solution: Applications of Osmotic Stress and Structure-Based Calculations.S.H. White, W.C. Wimley, A.S. Ladokhin, and K. Hristova, Protein Folding in Membranes: Determining Energetics of Peptide-Bilayer Interactions.M.L. Doyle and P. Hensley, Tight Ligand Binding Affinities Determined from Thermodynamic Linkage to Temperature by Titration Calorimetry.I. Luque and E. Freire, Structure-Based Prediction of Binding Affinities and Molecular Design of Peptide Ligands.A.P. Minton, Molecular Crowding: Analysis of Effects of High Concentrations of Inert Cosolutes on Biochemical Equilibria and Rates in Terms of Volume Exclusion.J.M. Schwehm and W.E. Stites, Application of Automated Methods for Determination of Protein Conformational Stability.P. Beroza and D.A. Case, Calculations of Proton Binding Thermodynamics in Proteins.A.L. Klinger and G.K. Ackers, Analysis of Spectra from Multiwavelength Oxygen Binding Studies of Mixed Metal Hybrid Hemoglobins.L. Benazzi, R. Russo, M. Ripamonti, and M. Perrella, Study of the Bohr Effect in Hemoglobin Intermediates.P.W. Chun, Application of Planck-Benzinger Relationships to Biology.T.A. Morton and D.G. Myszka, Kinetic Analysis of Macromolecular Interactions Using Surface Plasmon Resonance Biosensors.B.M. Baker and K.P. Murphy, Prediction of Binding Energetics from Structure Using Empirical Parameterization.M.A. McLean, C. Di Primo, E. Deprez, G. Hui Bon-Hoa, and S.G. Sligar, Photoacoustic Calorimetry of Proteins.H.F. Fisher and J. Tally, Isoergonic Cooperativity: A Novel Form of Allostery.L. Indyk and H.F. Fisher, Theoretical Aspects of Isothermal Titration Calorimetry.V.A. Bloomfield and I. Rouzina, Use of Poisson-Boltzmann Equation to Analyze Ion Binding to DNA.B. Sclavi, S. Woodson, M. Sullivan, M. Chance, and M. Brenowitz, Following the Folding of RNA with Time-Resolved Synchrotron X-Ray Footprinting.D.F. Senear, L.T. Perini, and S.A. Gavigan, Analysis of Interactions Between CytR and CRP at CytR-Regulated Promoters.D. Beckett, Energetic Methods to Study Bifunctional Biotin Operon Repressor.E.K. Merabet, D.S. Burz, and G.K. Ackers, Thermal Melting Properties of C-Terminal Domain Mutants of Bacteriophage l cI Repressor.J.T. Mason, Investigation of Phase Transitions in Bilayer Membranes.T.M. Laue, H.K. Shepard, T.M. Ridgeway, T.P. Moody, and T.J. Wilson, Membrane-Confined Analytical Electrophoresis.Author Index.Subject Index.