Endosome Signalling Part A book cover

Endosome Signalling Part A

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the first of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the endosomal compartment by multi-parametric image analysis, assessment of peptide internalization and endosomal signaling, and VEGF-A in endosomal signaling.


Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Included in series
Methods in Enzymology

Hardbound, 412 Pages

Published: January 2014

Imprint: Academic Press

ISBN: 978-0-12-397926-1


  • Section I.  COMPARTMENTS
    1. Multivesicular endosome biogenesis
      Andreas Brech
    2. An anomalous endocytic compartment in fibroblasts from Sandhoff disease patients
      Carla Emiliani
    3. Visualizing of signaling proteins on endosomes using Knock Down and Rescue approach
      Emilia Galperin
    4. Direction of viral infections to unproductive compartments in endosomal signaling
      Richard G. Hegele
    5. Zinc in and out of organelles of the secretory and endosomal-lysosomal system
      Taiho Kambe
    6. Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during C. elegans development
      Renaud Legouis
    7. Assessment of cation trapping by cellular acidic compartments
      Francois Marceau
    8. Signaling from inside as initiated by the secretory compartments
      Michele Sallese
    9. Recycling endosomal receptors
      Matthew N. J. Seaman

    10. Polarity proteins and endosomal protein trafficking and signaling
      C. Yan Cheng
    11. Membrane trafficking pathway from recyling endosomes to lysosomes
      Mitsunori Fukuda
    12. Measurement of intercellular transfer to signaling endosomes
      Jennifer Gillette
    13. Measurement of bidirectional transport between the trans-Golgi network and the endosomal system
      Bernard Hoflack
    14. Mutant mice with defects in P1(3.5)P2 biosynthesis and endosome/lysosome trafficking
      Miriam H. Meisler
    15. Endosomal trafficking of the somatostatin receptor 3
      Elizabeth S. Sztul

    Section III.  PROTEINS
    16. Notch
      Spyros Artavanis-Tsakonas
    17. Endocytic regulation of notch signaling during development
      Marcos Gonzalez-Gaitan
    18. Tollip participates in intracellular transport via endosomes
      Yoriko Atomi
    19. PX-FERM proteins
      Brett M. Collins


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