Enantioselective Chemical Synthesis book cover

Enantioselective Chemical Synthesis

Methods, Logic, and Practice

Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field’s progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource.

  • In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists.
  • Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level.
  • Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules

Audience

Third year undergraduates, graduates, post-doctorates, and professionals interested in the synthesis of chiral molecules

Hardbound, 334 Pages

Published: October 2013

Imprint: Academic Press

ISBN: 978-0-615-39515-9

Contents

  • Part 1 – Tools for enantioselective synthesis
    Tools for enantioselective synthesis
    Formation of C-H Bonds
    Formation of C-O Bonds
    Addition of H-Y (Y=B, Si, CO, CN, vinyl) to C=C
    Formation of C-C Bonds
    Cyclization
    Part 2 – Planning enantioselective syntheses
    Part 3 – Enantioselective multi-step synthesis: examples

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