Emerging Targets & Therapeutics in the Treatment of Psychostimulant Abuse

Edited by

  • Linda P. Dwoskin, Pharmaceutical Education, College of Pharmacy, University of Kentucky, Lexington, KY, USA

This new volume of Advances in Pharmacology presents the emerging targets and therapeutics in the treatment of psychostimulant abuse. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
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Pharmacologists, immunologists, and biochemists


Book information

  • Published: February 2014
  • ISBN: 978-0-12-420118-7

Table of Contents

1. Glial Modulators as Potential Treatments of Psychostimulant Abuse
 Patrick M. Beardsley and Kurt F. Hauser
2. The Vesicular Monoamine Transporter-2 (VMAT2): An Important Pharmacological Target for the Discovery of Novel Therapeutics to Treat Methamphetamine Abuse
 Justin R. Nickell, Kiran B. Siripurapu, Ashish Vartak, Peter A. Crooks & Linda P. Dwoskin
3. Customizing Monoclonal Antibodies for the Treatment of Methamphetamine Abuse: Current and Future Applications
 Eric C. Peterson, W. Brooks Gentry, and S. Michael Owens
4. Monoamine Transporter Inhibitors and Substrates as Treatments for Stimulant Abuse
 Leonard L. Howell and S. Stevens Negus
5. Bupropion and Bupropion Analogs as Treatments for CNS Disorders
 F. Ivy Carroll, Bruce E. Blough, S. Wayne Mascarella, Hernán A. Navarro, Ronald J. Lukas and M. Imad Damaj
6. The Role of Guanfacine as a Therapeutic Agent to Address Stress-related Pathophysiology in Cocaine Dependent Individuals
 Helen Fox and Rajita Sinha
7. Beyond Small Molecule SAR – Using the Dopamine D3 Receptor Crystal Structure to Guide Drug Design
 Thomas M. Keck, Caitlin Burzynski, Lei Shi and Amy Hauck Newman
8. Dopamine D4 Receptors in Psychostimulant Addiction
 Patricia Di Ciano, David Grandy and Bernard Le Foll
9. Sigma Receptors as Potential Therapeutic Targets to Mitigate Psychostimulant Effects
 Rae R. Matsumoto, Linda Nguyen, Nidhi Kaushal and Matthew J. Robson
10. Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence
 Jean M. Bidlack
11. The Combination of Metyrapone and Oxazepam for the Treatment of Cocaine and Other Drug Addictions
 Nicholas E Goeders, Glenn F Guerin and Christopher D Schmoutz
12. Salvinorin A Analogs and Other Kappa Opioid Receptor Compounds as Treatments for Cocaine Abuse
 Bronwyn M Kivell, Amy WM Ewald and Thomas E Prisinzano
13. Nicotinic Receptor Antagonists as Treatments for Nicotine Abuse
 Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
14. New Directions in Nicotine Vaccine Design and Use
 Paul R. Pentel and Mark G. LeSage
15. Bath Salts, Mephedrone, and Methylenedioxypyrovalerone as Emerging Illicit Drugs That Will Need Targeted Therapeutic Intervention
 Richard A. Glennon