E. coli
Genomics, Evolution and Pathogenesis
Edited by- Michael Donnenberg, University of Maryland School of Medicine, Baltimore, U.S.A.
- Michael Donnenberg, University of Maryland School of Medicine, Baltimore, U.S.A.
Escherichia coli: Virulence Mechanisms of a Versatile Pathogen is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Escherichia coli: Virulence Mechanisms of a Versatile Pathogen concludes with a presentation of virulence factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.
Audience
Microbiologists, cell biologists, infectious disease clinicians, food safety experts, veterinarians, and advanced students.
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Published: September 2002
Imprint: Academic Press
ISBN: 978-0-12-220751-8
Reviews
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"...a thorough, timely treatise on the current state of the field for researchers and advanced graduate students in bacterial pathogenesis. It is also an excellent and valuable reference work of general interest to microbiologists, infectious disease specialists, and food safety experts, and should be included in microbiology and medical reference libraries."-ASM NEWS (June 2003) "...a very informative book which is well presented and would be excellent value for money for scientists generally interested in the basis of microbial pathogenesis, as well as E. coli specifically."-MICROBIOLOGY TODAY (August 2003)
Contents
- Introduction. SECTION ONE: E. coli THE ORGANISMThe genomes of E. coli K-12 and pathogenic E. coli. The evolution of pathogenic E. coli. SECTION TWO: E. coli PATHOTYPESEnteropathogenic E. coli.Enterotoxigenic E. coli.Enteroaggregative and Diffuse-Adhering E. coli.Shigella and Enteroinvasive E. coli.Uropathogenic E. coli.Meningitis-associated E. coli.SECTION THREE: E. coli VIRULENCE FACTORS Adhesive Pili of the Chaperone-Usher Family.Type IV Pili.Type III Secretion.Hemolysin.Capsule and Lipopolysaccharide.
