Drug Monitoring and Clinical Chemistry
- Georg Hempel, Institut für Pharmazeutische und Medizinische Chemie Westfälische Wilhelms-Universität Münster.
Analysts working on drug analysis in clinical chemistry, hospital pharmacists involved in therapeutic drug monitoring, other pharmacists, chemists or physicians working on pharmacokinetic studies in industry or academia.
- Published: May 2004
- Imprint: ELSEVIER
- ISBN: 978-0-444-50972-7
"Altogether this is an important book, with many leading scientists as co-authors. It should be an important reference book for scientists, analytical chemists and clinicians working in this and related fields."
Å. Norstrom, CLINICAL PHARMACOLOGY, Volume 60, no. 12, Feb. 2005
"very useful to those readers who wish to become up-to-date on recent developments and trends, as well as to those who are new-comers to the field".
Vasant Ranade, PhD, AMERICAN JOURNAL OF THERAPEUTICS, 2005
Table of ContentsSample preparation for the analysis of drugs in biological fluids (Yoshihiro Saito et al.).
Chromatographic methods for the analysis of drugs in biological fluids (Hassan Y. Aboul-Enein et al).
Capillary electrophoresis for the determination of drugs in biological fluids (Zakariya K. Shihabi).
Immunoassays for the therapeutic drug monitoring and clinical toxicology (W. Clarke).
Validation of bioanalytical methods (S. Berthier).
Pharmacokinetic methods for the analysis, interpretation and management of TDM data, and for individualising drug dosage regimens optimally (R. Jelliffe et al.).Dose and therapy individualisation in cancer chemotherapy (G. Hempel).
Rationale and utility of therapeutic drug monitoring for the optimisation of antibiotic therapy (C. Ong, D.P. Nicolau).
Therapeutic drug monitoring of antiepileptic drugs(S.I. Johannessen).
Therapeutic drug monitoring of antipsychotic and antidepressant drugs (P.B. Mitchell).
Monitoring immunosuppressant drugs (D.W Holt, A. Johnston).
Pharmacogenomics: methodologies for genotyping and phenotyping (P. Jannetto et al.).
Applications of genotyping and phenotyping for clinically relevant polymorphisms of drug metabolizing enzymes and drug transportersA. Lazar et al.).