Diffusion MRI

From Quantitative Measurement to In vivo Neuroanatomy

Edited by

  • Heidi Johansen-Berg, Oxford Centre for Functional MRI of the Brain (FMRIB), Department of Clinical Neurology, University of Oxford, UK
  • Timothy E.J. Behrens, Department of Experimental Psychology, University of Oxford; Centre for Functional MRI of the Brain (FMRIB), UK

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

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Neuroscientists interested in the study of connections in the brain, brain imaging, within Cognitive Neuroscience, Neuroscience, Radiology, Medical Physics and adjacent areas.


Book information

  • Published: November 2013
  • ISBN: 978-0-12-396460-1

Table of Contents

Section I: Introduction to Diffusion MRI
1. Introduction to diffusion MR
2. Pulse Sequences for Diffusion-Weighted MRI
3. Diffusion Acquisition: Pushing the Boundaries
4. Geometric Distortions in Diffusion MRI
5. Gaussian Modeling of the Diffusion Signal
6. Multiple Fibers: Beyond the Diffusion Tensor

Section II: Diffusion MRI for Quantitative Measurement
7. White Matter Structure: A Microscopist's View
8. The Biological Basis of Diffusion Anisotropy
9. Inferring Microstructural Information of White Matter from Diffusion MRI
10. Cross-Subject Comparison of Local Diffusion MRI Parameters
11. Diffusion MRI in Neurological Disorders
12. Diffusion Tensor Imaging in the Study of Aging and Age-Associated Neural Disease
13. Diffusion Imaging in teh Developing Brain
14. Individual Differences in White Matter Microstructure in the Healthy Brain
15. Diffusion Tensor Imaging and its Applications to Schizophrenia and Related Disorders

Section III: Diffusion MRI for In Vivo Neuroanatomy
16. Mapping Connections in Humans and Non-Human Primates: Aspirations and Challenges for Diffusion Imaging
17. Classic and Contemporary Neural Tract-Tracing Techniques
18. The Human Connectome: Linking Structure and Function in the Human Brain
19. MR Diffusion Tractography
20. Validation of Tractography
21. Connectivity Fingerprinting of Gray Matter
22. Contribution of Diffusion Tractography to the Anatomy of Language
23. Presurgical Tractography Applications
24. Comparing Connections in the Brains of Humans and Other Primates Using Diffusion-Weighted Imaging
25. Imaging Structure and Function