Diagnostic Pathology: Cytopathology book cover

Diagnostic Pathology: Cytopathology

Featuring a highly accessible, easy-to-read format, Diagnostic Pathology: Cytopathology is written with the busy cytopathology professional in mind. "Key Facts" at the beginning of each chapter highlight the quick criteria needed for diagnosis or adequacy evaluation at the time of a procedure, while comprehensive coverage throughout the rest of the chapter is written in a consistent, succinct way to facilitate learning.

Hardbound, 808 Pages

Published: February 2014

Imprint: Amirsys

ISBN: 978-1-931884-55-6

Contents

  • PART 1: GYNECOLOGIC CYTOPATHOLOGY

    SECTION I: OVERVIEW

    Pap Test: History and Reporting Terminology

    Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology

    Specimen Adequacy in Cervicovaginal Cytology

    SECTION II: BENIGN AND INFECTIOUS CONDITIONS

    Normal Pap Test

    Infectious and Other Organisms in Pap Tests

    Benign/Other Nonneoplastic Findings

    Other Benign Mimics and Artifacts

    SECTION III: SQUAMOUS CELL ABNORMALITIES AND MIMICS

    Low-Grade Squamous Intraepithelial Lesion and Mimics

    High-Grade Squamous Intraepithelial Lesion and Mimics

    Atypical Squamous Cells of Undetermined Significance

    Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion

    Squamous Cell Carcinoma of Cervix, Variants and Mimics

    SECTION IV: GLANDULAR CELL ABNORMALITIES AND MIMICS

    Endocervical Adenocarcinoma In Situ, Variants and Mimics

    Endocervical Adenocarcinoma, Variants and Mimics

    Adenocarcinoma, Minimal Deviation

    Endometrial Cancers: Usual Types, Variants, and Mimics

    Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS

    Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy

    SECTION V: EXTRAUTERINE CARCINOMAS AND OTHER MALIGNANCIES OF FEMALE GENITAL TRACT

    Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology

    Small Cell Neuroendocrine Carcinoma of Cervix

    Other Uncommon Malignancies in Cervicovaginal Cytology

    SECTION VI: MOLECULAR TESTING IN GYNECOLOGIC CYTOLOGY

    HPV and Other Molecular Testing in Gynecologic Cytology

    SECTION VII: DIRECTLY SAMPLED ENDOMETRIAL CYTOLOGY

    Directly Sampled Endometrial Cytology

    SECTION VIII: ANAL CYTOLOGY

    Anal Cytology

    PART 2: EXFOLIATIVE CYTOPATHOLOGY

    SECTION I: RESPIRATORY TRACT INCLUDING LUNG FNAS

    Specimen Types in Respiratory Cytology and Adequacy Criteria

    Benign and Reactive Changes

    Pneumocystis Pneumonia and Mimics

    Fungal Organisms in Respiratory Cytology

    Parasitic Organisms in Respiratory Cytology

    Viral Infections (Cytomegalovirus, Herpesvirus, and Others)

    Mycobacteria and Other Bacterial Infections

    Sarcoidosis and Other Immune-Related Conditions

    Pulmonary Alveolar Proteinosis and Mimics

    Miscellaneous Findings Including Contaminants

    Adenocarcinoma

    Squamous Cell Carcinoma

    Small Cell Carcinoma

    Large Cell Neuroendocrine Carcinoma

    Carcinoid and Atypical Carcinoid

    Rare Benign and Low Malignant Potential Tumors

    Rare Malignant Tumors

    Pulmonary Lymphoma

    Pulmonary Metastasis

    SECTION II: GASTROINTESTINAL TRACT

    Specimen Types in Gastrointestinal Cytology and Normal Cellular Components

    Parasitic Infections

    Viral Infections

    Esophagitis and Barrett Esophagus

    Esophageal Adenocarcinoma

    Esophageal Squamous Cell Carcinoma

    Gastritis and Intestinal Metaplasia

    Gastric Adenocarcinoma

    Gastric Lymphoma

    Ampulla/Bile Duct/Pancreatic Duct Reactive Changes

    Ampulla/Bile Duct/Pancreatic Duct Adenocarcinoma

    Colorectal Adenoma/Carcinoma

    Neuroendocrine Tumor/Carcinoma

    SECTION III: CEREBROSPINAL FLUID

    Normal Cerebrospinal Fluid and Contamination by Normal Elements

    Infectious Meningitis

    Aseptic and Mollaret Meningitis

    Subarachnoid Hemorrhage

    Neurodegenerative Diseases

    Primary Brain Tumors

    Leukemia and Lymphoma

    Metastasis in CSF

    SECTION IV: PLERUAL, PERITONEAL, PERICARDIAL, AND PELVIC FLUID AND WASHINGS

    Normal Cellular Components and Reactive Mesothelial Proliferations

    Infectious Conditions

    Autoimmune Diseases

    Malignant Effusion, Mesothelioma

    Malignant Effusion, Carcinomas

    Malignant Effusion, Sarcomas

    Lymphoid Effusions and Lymphomas

    Primary Effusion Lymphoma

    Endometriosis and Endosalpingiosis

    Ovarian Neoplasms

    Immunocytochemistry, Histochemistry, and Other Ancillary Techniques

    SECTION V: URINARY CYTOLOGY

    Normal Urinary Cytology and Specimen Types

    Ileal Conduit Specimens

    Noninfectious Benign Conditions

    Infectious Benign Conditions

    Reactive Urothelial Changes

    Low-Grade Urothelial Lesions

    High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ

    Squamous Cell Carcinoma of Urinary Bladder

    Adenocarcinoma of Urinary Bladder

    Other Malignancies in Urinary Cytology

    Renal Pelvic Cytology

    Ancillary Testing, UroVysion, and Others

    PART 3: FINE-NEEDLE ASPIRATION, SUPERFICIAL

    SECTION I: OVERVIEW

    Superficial Aspiration Technique

    SECTION II: THYROID GLAND

    Ultrasound-Guided Thyroid Fine-Needle Aspiration

    Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy

    Adenomatous Nodule

    Chronic Lymphocytic/Hashimoto Thyroiditis

    Granulomatous Thyroiditis

    Graves Disease/Diffuse Toxic Goiter

    Pigmented Thyroid Lesions and Crystals

    Atypical (Follicular) Cells of Undetermined Significance

    Suspicious for Follicular Neoplasm

    Suspicious for Hürthle Cell Neoplasm

    Papillary Thyroid Carcinoma

    Papillary Thyroid Carcinoma Variants

    Medullary Thyroid Carcinoma

    Poorly Differentiated Thyroid Carcinoma

    Anaplastic Thyroid Carcinoma

    Thyroid Lymphoma

    Metastatic Carcinoma to Thyroid

    Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA

    SECTION III: PARATHYROID GLAND

    Parathyroid Cyst, Adenoma, and Carcinoma

    SECTION IV: LYMPH NODES

    Overview

    Indications for Aspiration and Techniques

    FNA Sample Prep and Triage in Evaluating Suspected Lymphoma

    Benign, Infectious, and Reactive Hyperplasia

    Inflammatory and Reactive Lymphoid Hyperplasia

    Granulomatous Lymphadenitis, Infectious and Sarcoid

    Rosai-Dorfman Disease

    Metastatic Malignancies

    Metastatic Malignancies (Carcinoma, Melanoma)

    HPV-Related Head and Neck Squamous Cell Carcinoma

    Nodal B-Cell Lymphoma

    Small Lymphocytic Lymphoma

    Lymphoplasmacytic Lymphoma

    Mantle Cell Lymphoma

    Nodal Marginal Zone Lymphoma

    Follicular Lymphoma

    Burkitt Lymphoma

    Large B-Cell Lymphoma

    Extranodal B-Cell Lymphoma

    Plasmacytoma

    Mediastinal Large B-Cell Lymphoma

    Plasmablastic Lymphoma

    T-Cell Lymphoma

    Peripheral T-Cell Lymphoma

    Mycosis Fungoides

    Angioimmunoblastic Lymphoma

    ALK(+) Anaplastic Large Cell Lymphoma

    T-Cell Lymphoblastic Lymphoma

    Hodgkin Lymphoma

    Nodular Lymphocyte-Predominant Hodgkin Lymphoma

    Classical Hodgkin Lymphoma

    SECTION V: SALIVARY GLAND

    Overview

    Approach to Interpretation of Salivary Gland Aspiration Biopsies

    Benign Lesions

    Normal Salivary Gland and Sialadenitis on Aspiration

    Cysts

    Pleomorphic Adenoma

    Warthin Tumor

    Other Benign Neoplasms

    Malignant Neoplasms

    Adenoid Cystic Carcinoma

    Acinic Cell Carcinoma

    Mucoepidermoid Carcinoma

    Basaloid Neoplasms, Benign and Malignant

    Carcinoma Ex Pleomorphic Adenoma

    Adenocarcinoma, Not Otherwise Specified

    Polymorphous Low-Grade Adenocarcinoma

    Salivary Duct Carcinoma

    Metastatic Carcinoma

    Primary and Metastatic Nonepithelial Tumors

    SECTION VI: BREAST

    Overview

    Role of Fine-Needle Aspiration of Breast,Techniques and Triple Test

    Benign Breast Lesions

    Inflammatory and Granulomatous Conditions

    Fat Necrosis

    Nonproliferative and Proliferative Changes in Breast

    Radial Scar/Complex Sclerosing Lesion

    Gynecomastia

    Mucocele-Like Lesion

    Benign Neoplasms

    Fibroadenoma

    Granular Cell Tumor of Breast

    Papillary Neoplasms

    Myofibroblastoma

    Malignant Neoplasms

    Ductal Carcinoma and Variants of Invasive Mammary Carcinoma

    Lobular Carcinoma

    Phyllodes Tumor

    Angiosarcoma and Other Sarcomas

    Lymphomas and Metastatic Tumors

    Nipple Discharge

    Cytology Specimens for Risk Assessment of Breast Cancer

    PART 4: FINE-NEEDLE ASPIRATION, DEEP ORGANS AND TISSUES

    SECTION I: OVERVIEW

    Techniques and Modalities of Deep Aspiration Biopsies

    SECTION II: MEDIASTINUM

    Overview

    Anatomic Compartments and Constituent Tumors

    Nonneoplastic Lesions

    Mediastinal Cysts and Inflammatory Lesions

    Neoplasms

    Thymoma

    Thymic Carcinoma

    Germ Cell Tumors

    Neurogenic Tumors

    Metastatic Tumors

    SECTION III: LIVER

    Overview

    Cytology of Normal Liver

    Inflammatory and Infectious Conditions of Liver

    Benign Hepatic Neoplasms

    Hepatocellular Adenoma

    Focal Nodular Hyperplasia

    Hemangioma

    Malignant Neoplasms

    Hepatocellular Carcinoma

    Hepatoblastoma

    Liver Metastasis

    SECTION IV: KIDNEY

    Overview

    Cytology of Normal Kidney

    Nonneoplastic Lesions

    Renal Cysts

    Xanthogranulomatous Pyelonephritis/Malakoplakia

    Benign Neoplasms

    Angiomyolipoma

    Oncocytoma

    Metanephric Adenoma

    Metanephric Stromal Tumor

    Malignant Neoplasms

    Clear Cell Renal Cell Carcinoma

    Papillary Renal Cell Carcinoma

    Chromophobe Renal Cell Carcinoma

    Collecting Duct Carcinoma

    Mucinous Tubular and Spindle Cell Carcinoma of Kidney

    Renal Medullary Carcinoma

    Metastatic Tumors to Kidney

    Renal Lymphomas

    Primary Renal Sarcomas in Adults

    Nephroblastoma (Wilms Tumor)

    Clear Cell Sarcoma of Kidney

    Rhabdoid Tumor of Kidney

    Congenital Mesoblastic Nephroma

    Carcinoid Tumor

    Tumors of Renal Pelvis

    Urothelial Carcinoma

    SECTION V: ADRENAL GLAND

    Overview

    Cytology of Normal Adrenal Gland

    Adrenal Cortical Lesions

    Adrenal Cortical Adenoma

    Adrenal Cortical Carcinoma

    Metastatic Tumors to Adrenal Gland

    Adrenal Medullary Lesions

    Pheochromocytoma

    SECTION VI: PANCREAS

    Overview

    Cytology of Normal Pancreas

    Pancreatic Cytology Reporting Terminology and Other Nonneoplastic Entities

    Nonneoplastic Lesions

    Pancreatitis

    Neoplasms

    Serous Microcystic Adenoma

    Mucinous Cystic Neoplasm

    Intraductal Papillary Mucinous Neoplasm

    Solid Pseudopapillary Neoplasm

    Pancreatic Endocrine Tumor

    Pancreatic Ductal Adenocarcinoma

    Unusual Variants of Ductal Carcinoma

    Acinar Cell Carcinoma

    Lymphoma and Secondary Tumors of Pancreas

    SECTION VII: BONE

    Overview

    Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors

    Neoplasms

    Langerhans Cell Histiocytosis

    Osteoblastoma

    Osteosarcoma

    Chondromas of Bone and Soft Tissue

    Chondroblastoma

    Chondrosarcoma

    Ewing Sarcoma/Primitive Neuroectodermal Tumor

    Adamantinoma

    Chordoma

    Giant Cell Tumor

    Bone Lymphoma

    Metastatic Tumors

    SECTION VIII: SOFT TISSUE

    Overview

    Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions

    Adipocytic Tumors

    Benign Adipose Tissue Tumors

    Liposarcoma

    Fibroblastic/Myofibroblastic Lesions

    Fibrosarcoma

    Myofibroblastoma

    Myofibroblastic Sarcoma

    Fibrohistiocytic Tumors

    Giant Cell Tumor of Tendon Sheath

    Fibrohistiocytic Tumors

    Tumors of Muscle Origin

    Smooth Muscle Tumors

    Skeletal Muscle Tumors

    Vascular Tumors

    Hemangioma

    Epithelioid Hemangioendothelioma

    Angiosarcoma

    Other Tumors

    Other Reactive and Neoplastic Soft Tissue Entities, Including GIST

    Cutaneous and Adnexal Cytology

    Intramuscular Myxoma

    Synovial Sarcoma

    Epithelioid Sarcoma

    Alveolar Soft Part Sarcoma

    Clear Cell Sarcoma of Soft Tissue

    Desmoplastic Small Round Cell Tumor

    SECTION IX: OPTHALAMIC AND NEUROPATHOLOGY

    Approach to Ophthalmic Cytology

    Ophthalmic Cytopathology, Infectious

    Ophthalmic Cytopathology, Neoplastic

    Neuropathology Squash Preparations, Infectious

    Neuropathology Squash Preparations, Glial Neoplasms

    Neuropathology Squash Preparations, Nonglial Neoplasms

    PART 5: MANAGEMENT AND ANCILLARY TESTING

    SECTION I: CYTOPREPERATORY AND QUALITY MANAGEMENT

    Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology

    Quality Improvement and Risk Reduction in Cytopathology

    SECTION II: ANCILLARY TESTING

    Immunocytochemistry

    Molecular Techniques

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