Diabetes and the Nervous System book cover

Diabetes and the Nervous System

Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)

Clinical neurologists and research neuroscientists

Hardbound, 600 Pages

Published: November 2014

Imprint: Elsevier

ISBN: 978-0-444-53480-4


  • Part I: Clinical impact of diabetes on the nervous system

    Epidemiology. Clinical phenotype. (sensory and sensory-motor neuropathies). Focal and entrapment neuropathies. Plexopathy. Painful neuropathy-clinical aspects. Autonomic neuropathy-clinical aspects. Motor neuropathy-clinical aspects. Diabetic neuropathy and foot ulceration. Glucose intolerance and neuropathy. Diabetic neuropathy in children. Cognitive disorders. Cerebrovascular disease. CNS complications of hyperglycemia and .hypoglycemia. Neurological infections in diabetes. Management and diagnosis of psycho-social issues in diabetic neuropathy. Overview of diabetes management in patients with neurological disorders. Sexual dysfunction in diabetes.

    Part II: Diagnostic and therapeutic approaches to diabetic neurological complications

    Electrophysiology. Diabetic neuropathy and nerve structure. Cutaneous innervation. New diagnostic approaches. CNS imaging in cerebrovascular and white matter disease. Overview of neuropathy therapy. Methodology useful for conduct of clinical trials in diabetic polyneuropathy. Therapy for neurological disorders of the diabetic CNS.

    Part III: Fundamental studies of diabetic neuroscience

    Neurosciences of glucose homeostasis. Mechanisms of disease: Mitochondria. Mechanisms of disease: New molecular players/DRG. Mechanisms of disease: Schwann cells. Mechanisms of disease: Oxidative stress. Mechanisms of disease: Axon dysfunction. Mechanisms of disease: Growth factors. Motor neuropathy- experimental Ischemic neuropathy. Mechanisms of CNS dysfunction. Hypoglycemia. Painful neuropathy: Mechanisms. Painful neuropathy: Neuroimaging. Autonomic neuropathy-models.


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