Development of T Cell Immunity book cover

Development of T Cell Immunity

T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.

This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.

Audience

Researchers, professors and graduate students in immunology, biochemistry, molecular biology, biotechnology, and medicine.

Hardbound, 342 Pages

Published: September 2010

Imprint: Academic Press

ISBN: 978-0-12-381284-1

Reviews

  • PRAISE FOR THE SERIES:
    "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal


Contents

  • Development of T cell immunity

    1. The development of T cell immunity - Adrian Liston
    2. The evolution of T cell immunity

    3. Genome duplication and T cell immunity - Masanori Kasahara

    • Questions arising from "Genome duplication and T cell immunity" - Claude Perreault
    • Response to questions - Masanori Kasahara

    1. The origin and role of MHC class I-associated self peptides - Claude Perreault

    • Questions arising from "The origin and role of MHC class I-associated self peptides" - Masanori Kasahara
    • Response to questions - Claude Perreault

    Thymic requirements for T cell immunity

    1. Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation - Nancy Manley and Brian Condie
    2. Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia - Cedric S Tremblay, Thu Hoang and Trang Hoang
    3. T cell immunity in the periphery

    4. Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses - Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson

    • Commentary on "Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses" - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes

    1. Cellular and Molecular Requirements in Lymph Node and Peyer’s Patch Development - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
    2. T follicular helper cells during Immunity and Tolerance - Michelle A. Linterman and Carola G. Vinuesa
    3. Preventing T cell-dependent autoimmunity

    4. Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells - Paola Romagnoli and Joost P.M. van Meerwijk
    5. Molecular Mechanisms of Regulatory T cell Development and Suppressive Function - Jeong M. Kim

      • Is Foxp3 the master regulator of regulatory T cells? - Adrian Liston

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