Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear

Edited by

  • Raymond Romand, Institut de Clinique de la Souris and Institut de Biologie Moléculaire et Cellulaire Illkirch, France
  • Isabel Varela-Nieto, Instituto de Investigaciones Biomédicas "Alberto Sols," CSIC-UAM, Madrid, Spain

Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.
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Undergraduate and graduate students in biology, developmental biology, neuroscience, audiology and hearing sciences, university teachers as well as specialized medical professional such as otologists and specialists in certain areas of hearing sciences.


Book information

  • Published: November 2003
  • ISBN: 978-0-12-153157-7

Table of Contents

Reviews include:Molecular conservation and novelties in vertebrate ear developmentFormation of the outer and middle ear, molecular mechanismsMolecular basis of inner ear inductionFGF signaling in ear development and innervationThe roles of retinoic acid during inner ear developmentGrowth factors and early development of otic neurons