Development, Differentiation and Disease of the Para-Alimentary Tract

Edited by

  • Klaus Kaestner, Institute of Diabetes, Obesity & Metabolism, University of Pennsylvania School of Medicine, PA, USA

Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.
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Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.


Book information

  • Published: November 2010
  • ISBN: 978-0-12-385233-5


"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal

Table of Contents

  1. Transcriptional Control of Acinar Development and Homeostasis
  2. Raymond J. MacDonald, Galvin H. Swift, and Francisco X. Real

  3. Molecular Biology of Pancreatic Ductal Adenocarcinoma Progression:Aberrant Activation of Developmental Pathways
  4. Andrew D. Rhim and Ben Z. Stanger

  5. Transcriptional Control of Hepatocyte Differentiation
  6. Masato Nagaoka and Stephen A. Duncan

  7. Molecular Mechanisms of Biliary Development
  8. Frédéric P. Lemaigre

  9. Molecular determinants of liver zonation
  10. Cyril Torre, Christine Perret, and Sabine Colnot

  11. Fibrosis in the Liver: acute protection and chronic disease
  12. Youngmin Lee and Scott L. Friedman

  13. Hierarchies of transcriptional regulation during liver regeneration
  14. Svitlana Kurinna and Michelle Craig Barton

  15. Biology of the Adult Hepatic Progenitor Cell: "Ghosts in the Machine"
  16. Houda Darwiche and Bryon E. Petersen

  17. Signaling networks in human hepatocarcinogenesis - novel aspects and therapeutic options

K. Breuhahn, P. Schirmacher