Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract book cover

Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract

Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Hardbound, 292 Pages

Published: December 2010

Imprint: Academic Press

ISBN: 978-0-12-381280-3


    "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal


      1. Molecular regulation of vertebrate early endoderm development.
        Kim Tremblay
      2. Making boundaries: Separating intestine from stomach
        Deborah Gumucio
      3. Molecular Determinants of the Esophageal Epithelium
      4. Cdx genes, inflammation and the pathogenesis of Barrett's metaplasia.
        John Lynch
      5. Differentiation of the gastric mucosa
        Jason Mills
      6. Gastric Cancer Stem Cell
        Ramesh Shivdasani
      7. Oxyntic Atrophy and Gastric Cancer
        Jim Goldenring
      8. Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe?
        Juanita Merchant
      9. The Intestinal Stem Cell
        Calvin Kuo
      10. The role of the basement membrane as a modulator of intestinal epithelial-mesenchymal interactions
        Michele Kedinger
      11. Differentiation of Enteroendocrine Cells
        Andrew Leiter
      12. Controlling gene expression in the intestinal epithelium
        David Breault
      13. Inflammatory Bowel Disease, dysplacia and CRC
        Deborah Rubin
      14. Transcriptional Control of Exocrine Pancreas Development
        Ray MacDonald
      15. Molecular Basis of Pancreatic Cancer
        Ben Stanger
      16. Determinants of early liver development
        Klaus Kaestner
      17. Development of the Biliary Tree
        Frederic LeMaigre
      18. Transcriptional Control of Hepatic Differentiation
        Steve Duncan
      19. Fibrosis in the Liver: Acute protection and chronic disease
        Scott Friedman
      20. Adult Hepatic Progenitor Cells
        Bryon Petersen
      21. Molecular Determinants of Liver Zonation
        Sabine Colnot
      22. Signaling Pathways in Liver Development and Maintenance
        Satdarshan (Paul) Monga
      23. Cascades of transcription regulation during liver regeneration
        Michelle BARTON
      24. The Molecular Basis of Hepatocellular Carcinoma
        Peter Schirmacher



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