Desk Encyclopedia of General Virology book cover

Desk Encyclopedia of General Virology

This volume, derived from Encyclopedia of Virology, provides an overview of the development of virology during the last ten years.  Entries detail the nature, origin, phylogeny and evolution of viruses. It then moves into a summary of our understanding of the structure and assembly of virus particles and describes how this knowledge was obtained. Genetic material of viruses and the different mechanisms used by viruses to infect and replicate in their host cells are highlighted. The volume is rounded out with an overview of some major groups of viruses with particular attention being given to our current knowledge of their molecular biology.

Audience

virologists, microbiologists, immunologists, parasitologists working in research, teaching, industry and government

Hardbound, 672 Pages

Published: September 2009

Imprint: Academic Press

ISBN: 978-0-12-375146-1

Contents

  • Section 1. GENERAL TOPICS
    History of virology : bacteriophages
    History of virology :  plant viruses
    History of virology : vertebrate viruses
    Nature of viruses
    Origin of viruses
    Ribozymes
    Virus species
    Quasispecies
    Virus databases
    Phylogeny of viruses
    Evolution of viruses
    Taxonomy, classification and nomenclature of viruses
    Virus classification by pairwise sequence comparison
    Prions of vertebrates
    Viruses and bioterrorism

    Section 2. VIRIONS  
    Principles of virion structure
    Structure of non-enveloped virions
    Electron microscopy of viruses
    Cryo-electron microcopy
    Assembly of non-enveloped virions
    Assembly of enveloped virions
    Assembly of bacterial viruses
    Genome packaging of bacterial viruses
    Viral membranes
    Mimivirus

    Section 3. NUCLEIC ACIDS 
    Recombination
    Satellite nucleic acids and viruses
    Retrotransposons of vertebrates
    Defective interfering viruses
    Interfering RNAs
    Viruses as vectors in gene therapy 

    Section 4. VIRUS INFECTION 
    Viral receptors 
    Virus entry to bacterial cells
    Membrane  fusion
    Replication of viruses
    Persistent and latent viral infection
    Apoptosis and virus infection
    Viral pathogenesis
    Antiviral agents
    Diagnosis using serological and molecular approaches
    Diagnosis using microarrays
    Disease surveillance

    Section 5. IMMUNE RESPONSES
    Innate immunity
    Defeating innate immunity
    Antigen presentation
    Antigenicity and immunogenicity  of viral proteins
    Cytokines and chemokines
    Cell-mediated immunity to viruses
    Antibody - mediated immunity to viruses
    Orthomyxovirus antigen structure
    Antigenic variation
    Vaccine strategies
    DNA Vaccines
    Vaccine safety
    Neutralization of infectivity
    Immunopathology

    Section 6. DESCRIPTION AND MOLECULAR BIOLOGY OF SOME VIRUSES
    Adenoviruses : molecular biology
    Baculoviruses : molecular biology of granuloviruses
    Baculoviruses : molecular biology of nucleopolyhedroviruses
    Coronaviruses : molecular biology
    Hepatitis virus B : molecular biology
    Herpes simplex viruses : molecular biology
    Human cytomegalovirus : molecular biology
    Human immunodeficiency viruses : molecular biology
    Iridoviruses
    Kaposi’s sarcoma-associated herpesvirus : molecular biology
    Mononegavirales
    Nidovirales
    Nodaviruses
    Orthomyxoviruses : molecular biology
    Papillomaviruses  : molecular biology
    Partitiviruses
    Phycodnaviruses
    Picornaviruses
    Reoviruses  : molecular biology
    Seadornaviruses
    Tetraviruses
    Togaviruses : molecular biology

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