Current State of Alzheimer's Disease Research and Therapeutics

Edited by

  • Mary Lou Michaelis
  • Elias K. Michaelis

This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
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Pharmacologists, immunologists, and biochemists


Book information

  • Published: August 2012
  • ISBN: 978-0-12-394816-8

Table of Contents

      1. Hsp90 Modulation for the Treatment of Alzheimer’s Disease
      2. Huiping Zhao, Mary L. Michaelis and Brian S. J. Blagg

      3. Using Pittsburgh Compound B for In-vivo PET Imaging of Fibrillar Amyloid-beta
      4. Ann D. Cohen, Gil D. Rabinovici, Chester A. Mathis, William J. Jagust, William E. Klunk and Milos D. Ikonomovic

      5. Mitochondrial Abnormalities in Alzheimer's Disease: Possible Targets for Therapeutic Intervention
      6. Diana F. Silva, J. Eva Selfridge, Jianghua Lu, Lezi E, Sandra M. Cardoso, and Russell H. Swerdlow

      7. g-Secretase as a Target for Alzheimer’s Disease
      8. Michael S. Wolfe

      9. Altering Mitochondrial Dysfunction as an Approach to Treating Alzheimer’s Disease
      10. Jerry R. Colca and Douglas L. Feinstein

      11. scyllo-Inositol, Preclinical and Clinical Data for Alzheimers disease
      12. Keran Ma, Lynsie A.M. Thomason and JoAnne McLaurin

      13. Beyond Amyloid: The Future of Therapeutics for Alzheimer’s Disease
      14. Rachel F Lane, Diana W Shineman, John W Steele, Linda (Bobbi) H Lee and Howard M Fillit

      15. Activation of Protein Kinase C Isozymes for the Treatment of Dementias
      16. Miao-Kun Sun and Daniel L. Alkon

      17. STriatal Enriched Protein Tyrosine Phosphatase in Alzheimer’s Disease
      18. Jian Xu, Pradeep Kurup, Angus C. Nairn and Paul J. Lombroso

      19. Estrogen Regulation of Mitochondrial Bioenergetics: Implications for Prevention of Alzheimer’s Disease

Jia Yao and Roberta Diaz Brinton