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Current State of Alzheimer's Disease Research and Therapeutics

This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias.  With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

Audience
Pharmacologists, immunologists, and biochemists

Hardbound, 400 Pages

Published: August 2012

Imprint: Academic Press

ISBN: 978-0-12-394816-8

Contents

        1. Hsp90 Modulation for the Treatment of Alzheimer’s Disease
          2.

          Huiping Zhao, Mary L. Michaelis and Brian S. J. Blagg

        2. Using Pittsburgh Compound B for In-vivo PET Imaging of Fibrillar Amyloid-beta

          3. Ann D. Cohen, Gil D. Rabinovici, Chester A. Mathis, William J. Jagust, William E. Klunk and Milos D. Ikonomovic

        3. Mitochondrial Abnormalities in Alzheimer's Disease: Possible Targets for Therapeutic Intervention

          4. Diana F. Silva, J. Eva Selfridge, Jianghua Lu, Lezi E, Sandra M. Cardoso, and Russell H. Swerdlow

        4. g-Secretase as a Target for Alzheimer’s Disease

          5. Michael S. Wolfe

        5. Altering Mitochondrial Dysfunction as an Approach to Treating Alzheimer’s Disease

          6. Jerry R. Colca and Douglas L. Feinstein

        6. scyllo-Inositol, Preclinical and Clinical Data for Alzheimers disease

          7. Keran Ma, Lynsie A.M. Thomason and JoAnne McLaurin

        7. Beyond Amyloid: The Future of Therapeutics for Alzheimer’s Disease

          8. Rachel F Lane, Diana W Shineman, John W Steele, Linda (Bobbi) H Lee and Howard M Fillit

        8. Activation of Protein Kinase C Isozymes for the Treatment of Dementias

          9. Miao-Kun Sun and Daniel L. Alkon

        9. STriatal Enriched Protein Tyrosine Phosphatase in Alzheimer’s Disease

          10. Jian Xu, Pradeep Kurup, Angus C. Nairn and Paul J. Lombroso

        10. Estrogen Regulation of Mitochondrial Bioenergetics: Implications for Prevention of Alzheimer’s Disease

    Jia Yao and Roberta Diaz Brinton

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