Crystallography Made Crystal Clear

A Guide for Users of Macromolecular Models


  • Gale Rhodes, University of Southern Maine, Department of Chemistry, Portland, U.S.A.

Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.
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Audience is course named Macromolecular Crystallography, or Biological x-ray Crystallography. Enrollments range from 10--30 students in a major biochemistry or structural biology department. Primarily for Undergraduate and graduate students and non-expert crystallography professionals in biochemistry, biophysics, and molecular biology. All protein and nucleic acid researchers need to understand X-ray crystallography in enough detail to analyze, generalize, and communicate with others in the field. This topic is not adequately covered in most undergraduate programs or taken at the time by researchers who eventually become interested in it.


Book information

  • Published: February 2006
  • ISBN: 978-0-12-587073-3


Praise for the first edition " my opinion is now the best reference for noncrystallographers who want to know more about X-ray diffraction and the data that result from it." -AMERICAN JOURNAL OF PHYSIOLOGY

Table of Contents

Table of Contents 1. Model and Molecule 2. An Overview of Protein Crystallography 3. Protein Crystals 4. Collecting Diffraction Data 5. From Diffraction Data to Electron Data 6. Obtaining Phases 7. Obtaining and Judging the Molecular Model 8. A User's Guide to Crystallographic Models 9. Other Diffraction Methods 10. Other Kinds of Macromolecular Models 11. Tools for Studying Macromolecules