Contemporary Aspects of Biomedical Research

Drug Discovery

Edited by

  • S. J. Enna, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, USA
  • Michael Williams, Northwestern University, Chicago, IL, USA

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
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Audience

Pharmacologists, immunologists, and biochemists.

 

Book information

  • Published: November 2009
  • Imprint: ACADEMIC PRESS
  • ISBN: 978-0-12-378642-5

Reviews

PRAISE FOR THE SERIES
"...recommended not only to pharmacologists but also to all those in related disciplines"--NATURE
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."--H.E. Kaufmann in CHEMOTHERAPY
"Superb reading material."--JOURNAL OF PHARMACEUTICAL SCIENCES




Table of Contents

Drug Discovery - Michael Williams and S.J. Enna

Anti-inflammatory Agents as Cancer Therapeutics - Kho Kashfi

Proteasome Inhibitors in Oncology -  Bruce Ruggeri and Bruce Dorsey  

    TPA023: A Subtype-Selective GABAA Receptor Modulator with a Novel Pharmacological Profile - John Atack

    Problems with the Current Paradigm for Cancer Drug Development: How to Win This Game - Bharat B. Aggarwal

    New Approaches for the Treatment of Sleep Disorders - Andrew Winokur, Nick DeMartinis, and Jayesh Kamath

    Novel Strategies for Treating Hypercholesterolemia - Jerry Colca 

      Therapeutic Strategies for the Treatment of Drug Addiction - Jonathan Katz and Amy Newman

      Targets for Antihypertensives - David Taylor and Abdel Abdel-Rahman

      Metabotropic Glutamate Receptors as Targets for Antidepressants - Jeff Witkin

      New Approaches for the Treatment of Fibrosis - Alexander Scriabine.

      Preclinical Prerequisites for Antipsychotic Activity - Vincent Castagne, Paul C. Moser, and Roger Porsolt