Comprehensive Medicinal Chemistry II book cover

Comprehensive Medicinal Chemistry II

Volume 6: THERAPEUTIC AREAS I: Central Nervous System, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular

This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include CNS diseases (schizophrenia, anxiety, Alzheimer's), Pain, Metabolic syndrome (obesity, diabetes), Urogenital, Gastrointestinal (IBS) and Cardiovascular. Experts examine the key roles that medicinal chemistry and pharmacology play in reviving the fortunes of the drug discovery process and developing new treatment for each therapeutic areas.


For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.

Hardbound, 863 Pages

Published: November 2006

Imprint: Elsevier

ISBN: 978-0-08-044519-9


  • Volume 6 Therapeutic Areas I: Central Nervous System, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular
    Central Nervous System
    6.01 Central Nervous System Drugs Overview
    6.02 Schizophrenia
    6.03 Affective Disorders: Depression and Bipolar Disorders
    6.04 Anxiety
    6.05 Attention Deficit Hyperactivity Disorder
    6.06 Sleep
    6.07 Addiction
    6.08 Neurodegeneration
    6.09 Neuromuscular/Autoimmune Disorders
    6.10 Stroke/Traumatic Brain and Spinal Cord Injuries
    6.11 Epilepsy
    6.12 Ophthalmic Agents
    6.13 Pain Overview
    6.14 Acute and Neuropathic Pain
    6.15 Local and Adjunct Anesthesia
    6.16 Migraine
    Obesity/Metabolic Disorders/Syndrome X
    6.17 Obesity/Metabolic Syndrome Overview
    6.18 Obesity/Disorders of Energy
    6.19 Diabetes/Syndrome X
    6.20 Atherosclerosis/Lipoprotein/Cholesterol Metabolism
    6.21 Bone, Mineral, Connective Tissue Metabolism
    6.22 Hormone Replacement
    6.23 Urogenital Diseases/Disorders, Sexual Dysfunction and Reproductive
    Medicine: Overview
    6.24 Incontinence (Benign Prostatic Hyperplasia/Prostate Dysfunction)
    6.25 Renal Dysfunction in Hypertension and Obesity
    6.26 Gastrointestinal Overview
    6.27 Gastric and Mucosal Ulceration
    6.28 Inflammatory Bowel Disease
    6.29 Irritable Bowel Syndrome
    6.30 Emesis/Prokinetic Agents
    6.31 Cardiovascular Overview
    6.32 Hypertension
    6.33 Antiarrhythmics
    6.34 Thrombolytics


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