Comprehensive Medicinal Chemistry II

Volume 7: THERAPEUTIC AREAS II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology

Edited by

  • Jake Plattner, Anacor Pharmaceuticals Incorporated, Palo Alto, CA, USA
  • Manoj Desai, Gilead Sciences, Inc., Foster City, CA, USA

This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include Cancer (biology, chemotherapy, mechanism & target approaches), Infectious Diseases (viral [herpes, HIV], fungal, bacterial & parasitic), Inflammation & Immunology (arthritis, asthma) and Dermatology (acne, psoriasis). For each area experts examine the key roles that medicinal chemistry and pharmacology play in reviving the fortunes of the drug discovery process and developing new treatments. Ideal for students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.
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Audience

For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.

 

Book information

  • Published: November 2006
  • Imprint: ELSEVIER
  • ISBN: 978-0-08-044520-5


Table of Contents

Volume 7 Therapeutic Areas II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology
Anti Cancer
7.01 Cancer Biology
7.02 Principles of Chemotherapy and Pharmacology
7.03 Antimetabolites
7.04 Microtubule Targeting Agents
7.05 Deoxyribonucleic Acid Topoisomerase Inhibitors
7.06 Alkylating and Platinum Antitumor Compounds
7.07 Endocrine Modulating Agents
7.08 Kinase Inhibitors for Cancer
7.09 Recent Development in Novel Anticancer Therapies
Anti Viral
7.10 Viruses and Viral Diseases
7.11 Deoxyribonucleic Acid Viruses: Antivirals for Herpesviruses and Hepatitis B Virus
7.12 Ribonucleic Acid Viruses: Antivirals for Human Immunodeficiency Virus
7.13 Ribonucleic Acid Viruses: Antivirals for Influenza A and B, Hepatitis C Virus, and Respiratory Syncytial Virus
Anti Fungal
7.14 Fungi and Fungal Disease
7.15 Major Antifungal Drugs
Anti Bacterials
7.16 Bacteriology, Major Pathogens, and Diseases
7.17 β-Lactam Antibiotics
7.18 Macrolide Antibiotics
7.19 Quinolone Antibacterial Agents
7.20 The Antibiotic and Nonantibiotic Tetracyclines
7.21 Aminoglycosides Antibiotics
7.22 Anti-Gram Positive Agents of Natural Product Origins
7.23 Oxazolidinone Antibiotics
7.24 Antimycobacterium Agents
7.25 Impact of Genomics-Emerging Targets for Antibacterial Therapy
Drugs for Parasitic Infections
7.26 Overview of Parasitic Infections
7.27 Advances in the Discovery of New Antimalarials
7.28 Antiprotozoal Agents (African Trypanosomiasis, Chagas Disease, and Leishmaniasis)
I and I Diseases
7.29 Recent Advances in Inflammatory and Immunological Diseases: Focus on Arthritis Therapy
7.30 Asthma and Chronic Obstructive Pulmonary Disease
7.31 Treatment of Transplantation Rejection and Multiple Sclerosis
Dermatology
7.32 Overview of Dermatological Diseases
7.33 Advances in the Discovery of Acne and Rosacea Treatments
7.34 New Treatments for Psoriasis and Atopic Dermatitis