CNS Regeneration

Basic Science and Clinical Advances

Edited by

  • Jeffrey Kordower, Rush-Presbyterian Medical Center, Chicago, Illinois, U.S.A.
  • Mark Tuszynski, University of California, San Diego, U.S.A.

This second edition updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury.
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Neuroscientists and clinical research neurologists.


Book information

  • Published: December 2007
  • ISBN: 978-0-12-373994-0


Review of 1st edition "This is a well compiled and thoroughly edited and written text by the leaders in the field of neural excellent overview. Reasonably priced, this is a valuable addition to a neuroscientist's bookshelf." -Doody's Publishing Services, 4 Star Review

Table of Contents

CNS Regeneration, 2nd ed focuses on leading current neurological diseasemodels and methods for promoting central nervous system regeneration. The book reviewskey features of central nervous system injury and degeneration, then unites advances inneuroscience with novel medical strategies. Therapies that are currently being applied inclinical trials for stroke and spinal cord injury, as well as neurological diseases such as Parkinson’sdisease, Alzheimer’s disease, and Huntington’s disease, are reviewed by experts in thefield of basic and clinical neuroscience.Organized into multiple sections, section one focuses on responses of the nervous systemto cellular and axonal insults, identifying issues critical to mediating nervous system repair.Responses of neurons, axons, and glia to injury are described together with the deleteriouseffects of factors such as free radicals and excitotoxins. Section two identifies tools forpromoting regeneration of the CNS including neurotrophic factors, and primary and immortalizedpro-genitor cells. Subsequent chapters discuss the application of…Huntington’s disease,novel therapies for spinal…demyelination, and the design of clinical trials…in rehabilitationwith neural repair.This second edition provides some of the most current and promising approaches to understandingCNS regeneration generally, and to the application of these findings to treatment ofneurological diseases, stroke, and spinal cord injury. This editions includes new chapters onstem cell therapy for brain tumors and Parkinson’s Disease. Written by leaders in the fieldof neuronal regeneration, this will be a valuable addition to scientists and practitioners inneuroscience.Key features• Covers basic research and medical applications• Translates advances to treatment for specific disorders• Includes exciting advances in stem cell research and neurotrophic factors