Clinical Neurophysiology of Infancy, Childhood, and Adolescence


  • Gregory L. Holmes, MD, Professor of Neurology, Harvard Medical School, Boston; Director, Division of Clinical Neurophysiology and Epilepsy, Children's Hospital, Boston, MA
  • Solomon Moshé, MD, Albert Einstein College of Medicine, Bronx, NY, USA
  • H. Royden Jones, Jr., Children's Hospital, Boston, MA, USA

This one-of-a-kind reference is unique in its exclusive devotion to the clinical neurophysiology of children. Written by a stellar group of recognized authorities, it blends classical electrophysiological techniques such as EEG, EMG, and nerve conduction studies with today's most cutting-edge methods, including magnetic stimulation and magnetoencephalography. The result is the first comprehensive review of all clinical neurophysiological techniques used to treat children with neurological disorders. This stand-alone text is essential to anyone performs or interprets neurophysiologic tests on children.
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Neurologists, Child Neurologists, Clinical Neurophysiologists


Book information

  • Published: September 2005
  • ISBN: 978-0-7506-7251-1

Table of Contents


Basic Principles and Maturational Change

1. Basic Principles of Electroencephalography

2. Electroencephalography of the Newborn: Normal Features

3. Visual Analysis of the Neonatal Electroencephalogram

4. Normal Development of the Electroencephalogram: Infancy Through

5. Visual Analysis of the Pediatric Electroencephalogram

6. Clinical Neurophysiology of the Motor Unit in Infants and Children

7. Maturational Changes vis-à-vis Neurophysiology Markers and the
Development of Peripheral Nerves

8. Somatosensory Evoked Potentials in Pediatrics—Normal

9. Brainstem Auditory Evoked Potentials in Pediatrics—Normal

10. Visual Evoked Potentials in Pediatrics—Normal


Disorders of Cerebral Function

11. Age-Specific Seizure Disorders

12. Neurophysiology of Language and Behavioral Disorders in Children

13. Neonatal Electroencephalography: Abnormal Features

14. Drug Effects on the Human Electroencephalogram

15. Electroencephalography and Structural Disease of the Brain

16. Manifestations of Metabolic, Toxic, and Degenerative Diseases

17. Infectious Diseases

18. Head Trauma

19. Childhood Sleep-Wake Disorders

20. The Diagnosis of Brain Death

21. Ambulatory Electroencephalography

22. Electroencephalography in Evaluation for Epilepsy Surgery in Children

23. Long-Term Electroencephalogram and Video Monitoring

24. Intraoperative Neurophysiologic Monitoring Using Evoked Potentials

Abnormal Evoked Potentials

25. Somatosensory Evoked Potentials in Pediatrics—Abnormal

26. Brainstem Auditory Evoked Potentials in Pediatrics—Abnormal

27. Visual Evoked Potentials in Pediatrics—Abnormal


Neuromuscular Disorders

28. The Floppy Infant

29. Facial and Bulbar Weakness

30. Spinal Muscular Atrophies and Other Disorders of the Anterior Horn Cell

31. Plexopathies and Nerve Root Lesions

32. Focal Neuropathies in Children

33. Clinical Neurophysiology of Pediatric Polyneuropathies

34. Autonomic Testing in Childhood

35. Neuromuscular Transmission Defects

36. Muscle Disorders in Children: Neurophysiologic Contributions to
Diagnosis and Management

37. Neuromuscular Problems of the Critically Ill Neonate, Child, and Adolescent

38. The Interrelation of DNA Analysis with Clinical Neurophysiology in the Diagnosis of
Chronic Neuromuscular Disorder of Childhood


Other Neurophysiologic Techniques

39. Magnetoencephalography (MEG)

40. Transcranial Magnetic Stimulation: An Overview

41. Sphincter Dysfunction