Clinical Lipidology: A Companion to Braunwald

Clinical Lipidology: A Companion to Braunwald's Heart Disease

Clinical Lipidology, a companion to Braunwald’s Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.


Hardbound, 568 Pages

Published: October 2014

Imprint: Saunders

ISBN: 978-0-323-28786-9


  • Section 1 Basic Mechanisms

    1. Human Plasma Lipoprotien Metabolism

    2. Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins

    3. Absorption and Excretion of Intestinal Cholesterol and Other Sterols

    4. High-Density Lipoprotein Metabolism

    5. Lipoproteins: Mechanisms for Atherogenesis and Progression of Atherothrombotic Disease

    6. Impact of Rare and Common Genetic Variants on Lipoprotein Metabolism

    7. Lipoprotein Oxidation: Mechanisms and Biotheranostic Applications

    Section 2 Risk Assessment

    8. Cholesterol: Concentration, Ratio, and Particle Number

    9. High-Density Lipoprotein Cholesterol and Triglycerides in Coronary Heart Disease Risk Assessment

    10. Lipoprotein(a)

    11. Clinical Evaluation for Genetic and Secondary Causes of Dyslipidemia

    12. Use of High Sensitivity C-Reactive Protein for Risk Assessment

    13. Role of Lipoprotein-Associated Phospholipase A2 in Vascular Disease

    14. Emerging Assays

    15. Imaging Atherosclerosis for Risk Stratification by Cardiac Computed Tomography or Carotid Ultrasound

    Section 3 Therapy

    16. Overview of General Approach to Management of Elevated Low-Density Lipoprotein Cholesterol and Mixed Dyslipidemia, High Triglycerides, and Low High-Density Lipoprotein Cholesterol

    17. Treatment Guidelines Overview

    18. Dietary Patterns for the Prevention and Treatment of Cardiovascular Disease

    19. Exercise and Lipids

    20. Weight Loss

    21. Statins

    22. Bile Acid Sequestrants

    23. Cholesterol Absorption Inhibitors

    24. Niacin (Nicotinic Acid)

    25. Fibrates

    26. Omega-3 Fatty Acids

    27. Combination Therapy for Dyslipidemia

    28. Nutriceuticals and Functional Foods for Cholesterol Reduction

    29. Evolving Targets of Therapy: Cholesteryl Ester Transfer Protein Inhibition

    30. Evolving Targets of Therapy: Proprotein Convertase Subtilisin/Kexin 9 Inhibition

    31. Evolving Targets of Therapy: Inflammation as a Method to Predict and Prevent Cardiovascular Events

    32. Invasive Imaging Modalities and Atherosclerosis: Intravascular Ultrasound

    33. Noninvasive Imaging Modalities and Atherosclerosis: The Role of Ultrasound

    34. Noninvasive Imaging Modalities and Atherosclerosis: The Role of Magnetic Resonance Imaging and Positron Emission Tomography Imaging

    35. Special Patient Populations: Diabetes and Metabolic Syndrome

    36. Special Patient Populations: Women and Elderly

    37. Special Patient Populations: Children and Adolescents

    38. Special Patient Populations: Familial Hypercholesterolemia and other Severe Hypercholesterolemias

    39. Special Patient Populations: Acute Coronary Syndromes

    40. Special Patient Populations: Transplant Recipients

    41. Special Patient Populations: Chronic Kidney Disease

    42. Special Patient Populations: Lipid Abnormalities in High-Risk Ethnic Groups

    43. Special Patient Populations: Human Immunodeficiency Patients

    44. Therapeutic Targeting of High-Density Lipoprotein Metabolism


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