Clinical Diabetes


  • Vivian Fonseca, MD, MRCP, Professor of Medicine and Pharmacology, Director, Diabetes Program, Tullis-Tulane Chair in Diabetes, Section of Endocrinology, Tulane University Health Sciences Center, New Orleans, LA

This new volume, written and edited by some of the world's leading diabetes specialists, provides the practical information you need to care for your patients with diabetes. Covering such areas as lifestyle management, pharmacologic therapy, complications of diabetes, special populations and situations, and organization and delivery of diabetes care, the book offers concise, clinical advice on all aspects of diagnosis and its ongoing management. A visually appealing full-color format, with clinical algorithms, at-a-glance learning elements, and illustrations specially created for the book, makes this a highly convenient source for the practical guidance you need to manage your diabetic patients.
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Book information

  • Published: January 2006
  • Imprint: SAUNDERS
  • ISBN: 978-1-4160-0273-4

Table of Contents


* Introduction/Scope of the problem—The Diabetes/ Metabolic Epidemic
* Type I Diabetes—Genetics and Immunology
* Type 2 Diabetes—Insulin Resistance, Beta Cell Dysfunction and Other Metabolic/Hormonal Abnormalities
* Biochemical Consequences of Hyperglycemia, PKC, Aldose Reductase, DAG, Oxidative Stress, etc
* Pathogenesis and Consequences of Obesity
* The Metabolic Syndrome and its Effects on Cardiovascular Risk
* Endothelial Abnormalities in Diabetes

Lifestyle Management

* Preventing Diabetes—The Ultimate Management strategy: Lessons from the DPP
* Diets and Education—Making it Work
* Stress and Depression in Chronic Disease
* Exercise—Let’s Get Going

Pharmacological Therapy

* Insulin Secretagogues
* Insulin Sensitizers: Metformin and PPAR ligands
* Alpha Glucosidase Agents
* Comparing and Choosing Oral Agents—A Comprehensive Approach
* Managing Dyslipidemia
* Hypertension in Diabetes
* Optimal Insulin Strategies
* Beyond Insulin therapy—Other Hormonal Approaches
* Weight Loss Agents and Over-the-Counter Medications
* Insulin Pump therapy
* Blood Glucose Monitoring (Including CGMS/Noninvasive methods/ HbAic/ Fructosamine)
* Pancreas and Islet Transplant—What Every Physician Needs to Know


* Diabetic Ketoacidosis
* Hypoglycemia and its Management
* Diabetic Neuropathy (Including autonomic neuropathy and gastroparesis)
* Diabetic Nephropathy
* Erectile Dysfunction in Diabetes—An Endothelial Disorder
* The Diabetic Foot
* Managing Cardiovascular Disease and Events in the Patient with Diabetes
* Diabetic Retinopathy—Screening and Therapy

Pediatric Diabetes

* Type I Diabetes in Children and Adolescents
* Type II Diabetes in Children and Adolescents (including pediatric obesity)

Special Populations and Situations

* Diabetes and Pregnancy
* Inpatient Diabetes Management
* Diabetes in the Elderly
* Diabetes in African Americans
* Diabetes in Latinos
* New Drugs Causing Diabetes—HIV and Schizophrenia Treatment
* Surgery for Obesity—Potential Impact on Diabetesb

Organization and Delivery of Diabetes Care

* Running a Diabetes Clinic
* Costs and Cost-Control in Diabetes—Using the System to the Patient’s Advantage
* Effective Pharmacist Management in Diabetes

Tips and Trends

* Pearls from Major Clinical Trials—Practical Tips to Improve Outcomes: Important Lessons from the DCCT/ UKPDS/ ACCORD/ HOPE/ ALLHAT/ STENO etc.
* Trends in Diabetes and Obesity—Fear and Hope
Appendix—Insulin Regimens, Insulin Adjustment Guidelines