Cell and Tissue Based Molecular Pathology book cover

Cell and Tissue Based Molecular Pathology

A Volume in the Foundations in Diagnostic Pathology Series

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice!



Published: September 2008

Imprint: Churchill Livingstone

ISBN: 978-1-4377-1948-2



    Chapter 1 Molecular Biology Basics for the Pathologist, Ilka Warshawsky

    Chapter 2 Quality Assurance of Molecular Assays, Wayne W. Grody


    Chapter 3 Overview of Molecular Diagnostic Techniques and Instrumentation, Daniel H. Farkas and Carol A. Holland

    Chapter 4 Conventional and Real Time Polymerase Chain Reaction (PCR), Aaron Bossler and Vivianna Van Deerlin

    Chapter 5 Loss of Heterozygosity, Jennifer L. Hunt

    Chapter 6 Direct Genome Sequencing in Diagnostic Pathology, Gurunathan Murugesan and Gary W. Procop

    Chapter 7 Array-Based Comparative Genomic Hybridization in the Analysis of Genomic Alterations in Human Disease, Marek Skacel, Ana Ambu Siva, and Raymond R. Tubbs

    Chapter 8 Expression Arrays: Discovery and Validation, Neal Poulin and Torsten O. Nielsen

    Chapter 9 Epigenetics: DNA Hypermethylation in Cancer, Bin Yang

    Chapter 10 Tissue Microarrays, Ziad Peerwani

    Chapter 11 Fluorescence in Situ Hybridization, James R. Cook

    Chapter 12 Bright Field in Situ Hybridization, Ricardo V. Lloyd, Xiang Qian, and Long Jin

    Chapter 13 Immunoglobulin and T-Cell Receptor Gene Rearrangement, Margaret L. Gulley

    Chapter 14 Monitoring of Minimal Residual Hematologic Disease, Cuihong Wei, Jeffrey H. Lipton, and Suzanne Kamel-Reid

    Chapter 15 Molecular Detection of Circulating Tumor Cells, Karen L. Kaul

    Chapter 16 Intraoperative Molecular Staging Using Real-Time PCR, Tony E. Godfrey


    Chapter 17, Molecular Cytopathology, Karen S. Gustafson and Douglas P. Clark

    Chapter 18 Molecular Diagnosis of Infectious Agents in Tissue, Randall T. Hayden and Gary W. Procop

    Chapter 19 Molecular Neuropathology, Richard Prayson

    Chapter 20 Molecular Pathology of the Cardiovascular System, Carmela D. Tan and E. Rene Rodriguez

    Chapter 21 Molecular Pulmonary Pathology, Samuel Yousem and Sanja Dacic

    Chapter 22 Molecular Dermatopathology, Alexander J.F. Lazar, Jason W. Nash, and Abdul Hafeez Diwan

    Chapter 23 Molecular Gastrointestinal, Liver, and Pancreatic Pathology, Rish K. Pai, Rebecca Wilcox, and John Hart

    Chapter 24 Molecular Endocrine Pathology, Jennifer L. Hunt

    Chapter 25 Molecular Hematopathology, James R. Cook

    Chapter 26 Molecular Pathology of Bone and Soft Tissue Tumors, Brian P. Rubin, Alexander J.F. Lazar, and Andre Oliveira

    Chapter 27 Molecular Pathology of Breast Cancer, David G. Hicks

    Chapter 28 Molecular Genitourinary Pathology, Donna E. Hansel, Cristina Magi-Galluzzi, and Ming Zhou

    Chapter 29 Molecular Gynecologic Pathology, Monica Prasad Hayes, Edyta C. Pirog, and Lora Hedrick Ellenson

    Chapter 30 Pediatric Molecular Pathology, Robin LeGallo


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