Caveolae and Lipid Rafts : Roles in Signal Transduction & the Pathogenesis of Human Disease
Advances in Molecular and Cell Biology
- Philippe Frank
- Michael Lisanti
- Edward Bittar, Department of Physiology, University of Wisconsin Medical School, Madison, USA
Caveolae (latin for little caves) are small structures found at the surface of cells. They are responsible for the regulation of important metabolic pathway. As a consequence, they may play a critical role in several human diseases such as atherosclerosis, cancer, diabetes, and muscular dystrophies. This book analyzes the role and function of caveolae in these aspects and serves as the first textbook currently available on caveolae/caveolin.
Cell biologists, pharmaceutical researchers, and graduate level and medical students.