Cancer Theranostics book cover

Cancer Theranostics

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment.

Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives.

Audience

Industry and academia working on drug discovery/development, pharmacology, personalized medicine, nanomedicine, medical imaging, imaging guided therapy, biomarkers, molecular pathology, proteomics, genomics, microarray chips, molecular biology.

Hardbound, 544 Pages

Published: March 2014

Imprint: Academic Press

ISBN: 978-0-12-407722-5

Contents

  • Chapter 1: Introduction to Theranostics (Shawn Chen/Stephen Wang/Wolfgang Weber)

    Part I: In Vitro Theranostics (Editor: Stephen Wang)

    This part will discuss in vitro biomarkers (genomic, proteomic and metabolomic) that can predict cancer therapy response.

    Chapter 2: Introduction to theranostic biomarkers (Stephen Wong)

    Chapter 3: Genomics based theranostics (Hua Zoghbi/Federico Monzo/Trey Westbrook)

    Chapter 4: Proteomics based theranostics (Hanno Steen/Ching Lau/Paul Webb/Mauro Ferrari)

    Chapter 5: Metabolomics based theranostics (Willa Hsueh/John Baxter/Ke Ma/Matthew Heiden)

    Part II: Molecular Imaging (Editor: Wolfgang Weber)

    This part will discuss how molecular imaging techniques can be applied to image the functional and molecular changes during cancer treatment and thus monitor/predict early response to cancer therapy.

    Chapter 6: In vivo theranostic biomarkers (Hans Wester)

    Chapter 7: Radionuclide imaging of cancer therapy (Helmut Mäcke)

    Chapter 8: Optical imaging of cancer therapy (Vasilis Nziachristos)

    Chapter 9: MR imaging of cancer therapy (Jürgen Hennig)

    Chapter 10: Ultrasound imaging of cancer therapy (Fabian Kiessling)

    Chapter 11: Multimodality imaging of cancer therapy (Johannes Czernin)

    Part III: Imaging Guided Therapy (Editor: Stephen Wong)

    This part will discuss how molecular imaging and interventional radiology techniques in dealing with cancer patients.

    Chapter 12: Multimodality image-guided interventional systems (Kongkuo Lu/Zhong Xue)

    Chapter 13: CARS for cancer diagnosis (Zhiyong Wang/Marc Cicerone)

    Chapter 14: Multimodality image-guided treatment (investigators at JHMI/William Beaumont Hospital/University of Toronto)

    Chapter 15: Medical Robotics (Dan Stoianovici/Guangzhong Yang/Gabor Fichtinger)

    Part IV: Theranostic Platforms (Editor: Shawn Chen)

    This part will discuss various combinations of imaging and therapy platforms especially composite nanoparticles.

    Chapter 16: Optical imaging, PDT and PTT (Gang Zheng/Ick Chan Kwon)

    Chapter 17: MR imaging and AMF (Shouheng Sun/Miqin Zhang/Jin Xie)

    Chapter 18: Ultrasound and gene/drug delivery (Kathy Ferrara)

    Chapter 19: Imaging isotope/therapy isotope (Fan Wang/David Yang, MD Anderson)

    Chapter 20: Nobel metal nanoparticle platform (Younan Xia)

    Chapter 21: Carbon nanomaterial platform (Zhuang Liu/Hongjie Dai)

    Chapter 22: Silica nanoparticle platform (Leu-Wei Lo/Jeff Zink)

    Chapter 23: Quantum dot nanoparticle platform (Xiaohu Gao/Shuming Nie)

    Chapter 24: Polymer and protein platform (Zhe Wang/Xin Lin/Jinming Gao)

    Part V: Other (Editor: Shawn Chen)

    This part will discuss the practical issues with theranostics, such as the challenge of clinical translation and the market, as well as the future perspectives.

    Chapter 25: Clinical translation and regulations of theranostics (Mauro Ferrari)

    Chapter 26: Economy of theranostics (Omid Farokhzad/Bob Langer)

    Chapter 27: Future perspectives (Jinwoo Cheon/Sam Gambhir)

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