Calcium Regulation of Cellular FunctionEdited by
- Anthony Means, Duke University, Durham, North Carolina, U.S.A.
- Paul Greengard, Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University
- Angus Nairn, Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, U.S.A.
- Shirish Shenolikar, Durham, North Carolina, U.S.A.
Volume 30 examines the prominent role of calcium as an intracellular second messenger. Leading investigators review a wide variety of studies on how calcium enters and moves through cells, how it interacts with its many binding proteins, and how calcium and its intracellular receptor, calmodulin, control vital cellular processes. Coverage includes a detailed analysis of the mechanisms by which calcium bound to calmodulin regulates contractile proteins in smooth muscle cells. Close attention is given to the roles of calcium and calmodulin-dependent protein kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes, and control of cell division cycles. Other chapters discuss studies using genetically manipulable nonmammalian organisms to further proble the functions of calcium and calmodulin.
Advances in Second Messenger and Phosphoprotein Research
Hardbound, 416 Pages
Published: July 1998
Imprint: Academic Press