Brain Stimulation

Handbook of Clinical Neurology (Series editors: Aminoff, Boller, Swaab)

By
  • Andres Lozano, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Canada
  • Mark Hallett, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA

The field of brain stimulation is expanding rapidly.  Techniques such as deep brain stimulation (DBS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) arising from the research community are now becoming available for clinical diagnosis and treatment.  Clinical application is active in treating such disorders as Parkinson disease, dystonia and even depression.  The chapters written by leading international researchers and clinical specialists, includes coverage of techniques, modes of action and applications in physiology and therapeutics.  The combination of research and clinical coverage will be of interest to neurologists, neurosurgeons, psychiatrists, neuroscientists, and health care workers.

Hardbound, 550 Pages

Published: November 2013

Imprint: Elsevier

ISBN: 978-0-444-53497-2

Contents

  • Section 1: Basic science

    Excitability of neural tissues

    Animal Models of DBS

    DBS Surgical techniques

    How does DBS work

    Modelling the effects of DBS

    Therapeutic Stimulation versus ablation

    MRI safety of DBS

    Functional imaging (fMRI/PET)

    Clinical applications of DBS

    DBS for Parkinson’s disease -Patient selection

    DBS for Parkinson’s disease -Clinical outcome

    DBS for Parkinson’s disease -Adverse Effects

    Psychiatric considerations in DBS for PD

    DBS for Essential Tremor

    DBS for Primary Dystonia

    DBS for Secondary Dystonia

    DBS for other tremors, myoclonus, chorea

    DBS for Epilepsy

    DBS for Depression

    DBS for OCD

    DBS for Tourette’s Syndrome

    DBS for drug and alcohol dependency

    DBS for eating disorders

    DBS for Pain

    DBS for Minimally conscious states

    BS for cognitive disorders

    Ethical considerations of DBS

    PART 2: SUPERFICIAL BRAIN STIMULATION

    Section 1: Basic principles

    Types of stimulation, TES, TMS, rTMS, tDCS, coils, paradigms

    Epidural and subdural stimulation

    Physics of effects

    Biology of effects

    Section 2: Clinical utility in diagnosis

    Central motor conduction time

    Excitability studies (include drug effects)

    Section 3: Therapeutic uses

    Depression

    Other psychiatric uses

    Pain

    Tinnitus

    Parkinson’s disease

    Dystonia

    Epilepsy

    Rehabilitation (stroke)

    Section 4: Research applications

    Plasticity

    Parkinson’s disease

    Dystonia

    Huntington’s disease

    ALS

    Multiple sclerosis

    Migraine

    Dementia

    Addiction

    Tourette’s Syndrome

    Cerebellum

    Vision

    Somatic sensation

    Language

    Learning and Memory

    Cognition

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