Bone Substitute Biomaterials book cover

Bone Substitute Biomaterials

Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration.

Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms.


Bone Substitute Biomaterials provides a detailed review of this important area, and will be a helpful resource for scientists and engineers in both academia and the biomedical industry. It should be of particular interest to those working in orthopaedics and dentistry.

Hardbound, 352 Pages

Published: July 2014

Imprint: Woodhead Publishing

ISBN: 978-0-85709-497-1


  • Forward


    Part 1 Properties of bone substitute biomaterials in medicine

    1 Bone substitutes based on biomineralization
    S. Sprio, M. Sandri, S. Panseri, M. Iafisco, A. Ruffini, S. Minardi, A. Tampieri, Institute of Science and Technology for Ceramics, Italy

    2 Experimental quantification of bone mechanics
    P. Bhattacharya and G. H. van Lenthe, KU Leuven - University of Leuven, Belgium

    3 Osteoinductivization of dental implants and bone-defect-filling materials
    E. B. Hunziker, University of Bern, Switzerland  

    4 Bioresorbable bone graft substitutes
    T. J. Blokhuis, University Medical Center Utrecht, the Netherlands

    Part 2 Biomaterial substitute scaffolds and implants for bone repair

    5(19) Multi-functional scaffolds for bone regeneration
    V. Guarino, M. G. Raucci, A. Ronca, V. Cirillo and L. Ambrosio, National Research Council, IMCB and DSCTM, Italy

    6 3D bioceramic foams for bone tissue engineering
    K. K. Mallick and J. Winnett, University of Warwick, UK

    7 Titanium and NiTi foams for bone replacement
    A. Bansiddhi, Kasetsart University, Thailand and D. C. Dunand, Northwestern University, USA

    8 Bioceramics for skeletal bone regeneration
    G. C. Wang, Z. F. Lu and H. Zreiqat, The University of Sydney, Australia

    Part 3 Biomaterials for bone repair and regeneration

    9 Cartilage grafts for bone repair and regeneration
    C. S. Bahney and R. S. Marcucio, University of California, USA

    10 Chitosan for bone repair and regeneration
    J. Venkatesan and S. K. Kim, Pukyong National University, Republic of Korea 

    11 Inorganic polymer composites for bone regeneration and repair
    L. Grøndahl. K. S. Jack, and. C. S. Goonasekera, The University of Queensland, Australia

    12 Marine organisms for bone repair and regeneration
    S. A. Clarke and P. Walsh Queen’s University Belfast, UK


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