Biothiols, Part B: Glutathione and Thioredoxin: Thiols in Signal Transduction and Gene Regulation, 252

  • Helmut Sies, Institut Fur Physiologische Chemie, Germany
    • John Abelson, California Institute of Technology, Division of Biology, Pasadena, U.S.A.
      • Melvin Simon, California Institute of Technology, Division of Biology, Pasadena, U.S.A.


      Biochemists, molecular biologists, physiologists, cell biologists, and biomedical researchers.


Book information

  • Published: July 1995
  • ISBN: 978-0-12-182153-1


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Table of Contents

Glutathione: Distribution, Biosynthesis, Metabolism, and Transport:
D.P. Jones, Glutathione Distribution in Natural Products: Absorption and Tissue Distribution.
L.H. Lash, Intracellular Distribution of Thiols and Disulfides: Assay of Mitochondrial Glutathione Transport.
A. Meister, Glutathione Biosynthesis and Its Inhibition.
W.W. Wells, D.P. Xu, and M.P. Washburn, Glutathione: Dehydroascorbate Oxidoreductases.
F. Ursini, M. Maiorino, R. Brigelius-Flohé, K.D. Aumann, A. Roveri, D. Schomburg, and L. Flohé, Diversity of Glutathione Peroxidases.
D.J. Meyer and B. Ketterer, Purification of Soluble Human Glutathione S-Transferases.
H.J. Forman, M.M. Shi, T. Iwamoto, R.-M. Liu, and T.W. Robinson, Measurement of&ggr;-Glutamyl Transpeptidase and &ggr;-Glutamylcysteine Synthetase Activities in Cells.
T. Kondo, G.L. Dale, and E. Beutler, Thiol Transport from Human Red Blood Cells.
J.A. Fuchs, Glutathione Mutants.
D.J. Reed, Cystathionine.
T. Meier and R.D. Issels, Promotion of Cyst(e)ine Uptake.

Signal Transduction and Gene Regulation:
T.P. Holler and P.B. Hopkins, Ovothiols.
S.R. Hubbard, X-Ray Absorption Spectroscopy Studies of Protein Kinase C.
R. Gopalakrishna, Z.H. Chen, and U. Gundimeda, Modificiations of Cysteine-Rich Regions in Protein Kinase C Induced by Oxidant Tumor Promoters and Enzyme-Specific Inhibitors.
F.J. Romero and J. Romá, Glutathione and Protein Kinase C in Peripheral Nervous Tissues.
A.F.G. Quest, E.S.G. Bardes, W.Q. Xie, E. Willott, R.A. Borchardt, and R.M. Bell, Expression of Protein Kinase C&ggr; Regulatory Domain Elements Containing Cysteine-Rich Zinc-Coordinating Regions as Glutathione S-Transferase Fusion Proteins.
F.J.T. Staal, M.T. Anderson, and L.A. Herzenberg, Redox Regulation of Activation of NF-kB Transcription Factor Complex: Effects of N-Acetycysteine.
Y.J. Suzuki and L. Packer, Redox Regulation of DNA-Protein Interaction by Biothiols.
M. Mizuno and L. Packer, Suppression of Protooncogene C-fos Expression by Antioxidant Dihydrolipoic Acid.
M.S. Patel, N.N. Vettakkoruma-Kankav, and T.-C. Liu, Dihydrolipoamide Dehydrogenase: Activity Assays.

Thioredoxin and Glutaredoxin:
A. Holmgren and M. Björnstedt, S. Kumar, and A. Holmgren, Selenite and Selenodiglutathione: Reactions with Thioredoxin Systems.
R.S. Hutchison and D.R. Ort, Measurement of Equilibrium Midpoint Potentials of Thiol/Disulfide Regulatory Groups on Thioredoxin-Activated Chloroplast Enzymes.
J.H. Wong, K. Kobrehel, and B.B. Buchanan, Thioredoxin and Seed Proteins.
J.-P. Jacquot, E. Issakidis, P. Decottignies, M. Lemaire, and M.-M. Myroslawa, Analysis and Manipulation of Target Enzymes for Thioredoxin Control.
K. Schulze-Osthoff, H. Schenk, and W. Dröge, Effects of Thioredoxin on Activation Transcription Factor NF-KB.
M. Russel, Thioredoxin Genetics.
P. Schürmann, Ferredoxin: Thioredoxin System.
A. Holmgren and F. Åslund, Flutaredoxin.
H.J. Dyson, Nuclear Magnetic Resonance of Thioredoxin and Glutaredoxin.

Mimics of Biological Thiols and Thiol Inhibitors:
R.S. Glass and T.C. Stadtman, Selenophosphate.
M.-O. Christen, Anethole Dithiolethione: Biochemical Considerations.
M.-O. Christen, L. Fackir, and D. Jore, Use of Linoleic Acid Radiolysis for Assay of Antioxidant Action of Anethole Dithiolethione.
P. Rat, M.-O. Christen, M. Thevenin, J.-M. Warnet, and M. Adolphe, Cold Light Fluorimetry: A Microtritration Technology for Cell Culture to Evaluate Anethole dithiolethione and Other Biothiols.
H. Sies, Ebselen.
N. Sato, S. Iwata, A. Yamauchi, T. Hori, and J. Yodoi, Thiol Compounds and Adult T-Cell Leukemia Virus Infection: A Potential Therapeutic Approach.

Author Index.
Subject Index.