Biosensors: Kinetics of Binding and Dissociation Using Fractals


  • Ajit Sadana, Chemical Engineering Department, University of Mississippi, MS, USA

This title brings to the attention of researchers in the industry, and in academia, the application of fractals to help in modeling the analyte/receptor binding and dissociation kinetics on biosensor surfaces.The work builds on that done in Engineering Biosensors: Kinetics and Design Applications, published by Academic Press in 2002. In particular, more examples are provided of where biosensors may be effectively used. This sequel is extremely timely, given the anticipation that the applications and reliance on biosensors will increase due to the advances in miniaturization, (wireless) communications, and the development of new materials (especially biological and chemical). Other applications of biosensors on the increase can be found in: the protection of civilian structures and infrastructures; protection from possible biological and chemical threats; health care; energy; food safety; and the environment to name a few.
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Analytical Chemists, Biochemists, Biologists and Physical Chemists.


Book information

  • Published: December 2003
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-51512-4

Table of Contents

IntroductionInfluence of Reynolds Number on Fractal Binding Kinetics on a Surface-based BiosensorDNA Fractal Binding and Dissociation KineticsFractal Analysis of Binding and Dissociation Interactions of Estrogen Receptors to Ligands on Biosensor SurfacesFractal Analysis of Estrogen Receptor Binding and Dissociation Kinetics Fractal Analysis of Analyte-Estrogen Receptor Binding and DissociationFractal Analysis of Binding Interactions of Nuclear Estrogen Receptors Occurring On Biosensor SurfacesFractal Analysis of Cholera Toxin and Peptide-Protein Binding and Dissociation in BiosensorsThe Temporal Nature of the Binding and Dissociation Rate Coefficients and the Affinity Values for Biosensor Kinetics Fractal Analysis of Analyte-Receptor Binding and Dissociation, and Dissociation Alone for Biosensor ApplicationsFractal Analysis of Cellular Analyte-Receptor Binding and Dissociation on Biosensors Fractal Analysis of Analyte-Receptor Binding Kinetics on MicroarraysFractal Analysis of Cre-loxP Interactions and the Influence of Cl, O, and S on Drug/Liposome Interactions on BiosensorsFractal Analysis of Binding and Dissociation Kinetics on Randomly Coupled and Oriented Coupled Receptors on Biosensor Surfaces: Electrostatic EffectsFractal Analysis of Analyte-Receptor Binding and Dissociation on Biosensor Surfaces: Kinetics of Regeneration and Multiple Analyte Immunoassay (MAIA)Fractal Analysis of Analyte-Receptor Binding and Dissociation Kinetics in Microcantilever Biosensors