Biomaterials for Cancer Therapeutics

Diagnosis, Prevention and Therapy

Edited by

  • K Park, Purdue University, USA

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.

The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.

This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.
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Engineers/scientists working in the field of biomaterials with an emphasis on technologies for cancer; Researchers in pharmaceutical sciences, nanotechnologies, and related field


Book information

  • Published: October 2013
  • Imprint: Woodhead Publishing
  • ISBN: 978-0-85709-664-7


"On the whole, the book is a combination of the fundamentals of cancer biology, guiding principles on the design of biomaterials and the clinical potential of these biomaterials, which is of interest to a broad audience involving chemists, biologist and material scientists.", June 2014
"Intended for researchers, this collection introduces new methods for delivering drugs to cancer cells and tumors and innovative technologies for treating cancers with biomaterials. Needham …describes his low temperature-sensitive liposome (Thermodox) drug delivery system, which failed to meet its primary endpoint in a phase III trial of liver cancer.", February 2014

Table of Contents

Part 1 Fundamentals of biomaterials for cancer therapeutics: Introduction to biomaterials for cancer therapeutics; Cancer cell biology; Targeted drug delivery for cancer therapy. Part 2 Synthetic vaccines, proteins, and polymers for cancer therapeutics: Chemical synthesis of carbohydrate-based vaccines against cancers; Generating functional mutant proteins to create bioactive anti-cancer biopharmaceuticals; Polymer therapeutics for treating cancer. Part 3 Theranosis and drug delivery systems for cancer therapeutics: Nanotechnology for cancer screening and diagnosis; Synergistically integrated nanomaterials for multimodal cancer cell imaging; Hybrid nanocrystal as a versatile platform for cancer theranostics; Embolisation devices from biomedical polymers for intra-arterial occlusion and drug delivery in the treatment of cancer; Small Interfering RNAs (siRNAs) as Cancer Therapeutics; Reverse Engineering of Low Temperature Sensitive Liposome (LTSL) for treating cancer; Gold nanoparticles (GNPs) as multi-functional materials for cancer treatment; Multifunctional nanosystems for cancer therapy. Part 4 Biomaterial therapeutics and cancer cell interaction: Biomaterial strategies to modulate cancer; 3D cancer tumour models for evaluating chemotherapeutic efficacy; Nanotopography of biomaterials for controlling cancer cell function.