Biomarkers of Neurological and Psychiatric Disease

Hardbound, 470 Pages

Published: November 2011

Imprint: Academic Press

ISBN: 978-0-12-387718-5

Contents

  • 1. General overview: biomarkers in neuroscience research - Michaela D. Filiou and Christoph W. Turck
    2. Imaging brain microglial activation using positron emission tomography and translocator protein specific radioligands - David RJ Owen, Paul M Matthews
    3. The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders - Christopher H. Woelk, Akul Singhania, Josué Pérez-Santiago, Stephen J. Glatt, Ming T. Tsuang
    4. Proteomic technologies for biomarker studies in psychiatry: advances and needs - Daniel Martins-de-Souza, Paul C. Guest, Natacha Vanattou-Saifoudine, Laura W. Harris, Sabine Bahn
    5. Converging evidence of blood-based biomarkers for schizophrenia: an update - Man K.Chan, Paul C. Guest, Yishai Levin, Yagnesh Umrania, Emanuel Schwarz, Sabine Bahn, Hassan Rahmoune
    6. Abnormalities in metabolism and hypothalamic-pituitary-adrenal axis function in schizophrenia - Paul C Guest, Daniel Martins-de-Souza, Natacha Vanattou-Saifoudine, Laura W Harris, Sabine Bahn
    7. Immune and neuro-immune alterations in mood disorders and schizophrenia - Roosmarijn C Drexhage, Karin Weigelt, Nico van Beveren, Dan Cohen, Marjan A. Versnel, Willem A. Nolen Hemmo A. Drexhage
    8. Behavioural and molecular biomarkers in translational animal models for neuropsychiatric disorders - Zoltán Sarnyai, Murtada Alsaif, Sabine Bahn, Agnes Ernst, Paul C. Guest, Eva Hradetzky, Wolfgang Kluge, Viktoria Stelzhammer and Hendrik Wesseling
    9. Stem cell models for biomarker discovery in brain disease - Alan Mackay-Sim, George Mellick, Stephen Wood
    10. The application of multiplexed assay systems for molecular diagnostics - Emanuel Schwarz, Nico JM VanBeveren, Paul C. Guest, Rauf Izmailov, Sabine Bahn
    11. Algorithm development for diagnostic biomarker assays - Rauf Izmailov, Paul C. Guest, Sabine Bahn, Emanuel Schwarz
    12. Challenges of introducing new biomarker products for neuropsychiatric disorders into the market - Sabine Bahn, Richard Noll, Anthony Barnes, Emanuel Schwarz, Paul C Guest
    13. Towards personalized medicine in the neuropsychiatric field - Erik H.F. Wong, Jayne C. Fox, Mandy Y.M. Ng, Chi-Ming Lee
    14. Clinical utility of serum biomarkers for major psychiatric disorders - Nico JM van Beveren and Witte JG Hoogendijk
    15. The future: biomarkers, biosensors, neuroinformatics and e-neuropsychiatry - Christopher R Lowe

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